Neoantigen-specific stem cell memory-like CD4(+) T cells mediate CD8(+) T cell-dependent immunotherapy of MHC class II-negative solid tumors

CD4(+) T cells play key roles in a range of immune responses, either as direct effectors or through accessory cells, including CD8(+) T lymphocytes. In cancer, neoantigen (NeoAg)-specific CD8(+) T cells capable of direct tumor recognition have been extensively studied, whereas the role of NeoAg-spec...

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Detalles Bibliográficos
Autores principales: Brightman, Spencer E., Becker, Angelica, Thota, Rukman R., Naradikian, Martin S., Chihab, Leila, Zavala, Karla Soria, Ramamoorthy Premlal, Ashmitaa Logandha, Griswold, Ryan Q., Dolina, Joseph S., Cohen, Ezra E. W., Miller, Aaron M., Peters, Bjoern, Schoenberger, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382322/
https://www.ncbi.nlm.nih.gov/pubmed/37400675
http://dx.doi.org/10.1038/s41590-023-01543-9

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