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In vivo evaluation of a novel (18)F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain

PURPOSE: [(18)F]SF51 was previously found to have high binding affinity and selectivity for 18 kDa translocator protein (TSPO) in mouse brain. This study sought to assess the ability of [(18)F]SF51 to quantify TSPO in rhesus monkey brain. METHODS: Positron emission tomography (PET) imaging was perfo...

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Detalles Bibliográficos
Autores principales: Yan, Xuefeng, Siméon, Fabrice G., Liow, Jeih-San, Morse, Cheryl L., Montero Santamaria, Jose A., Jenkins, Madeline, Manly, Lester S., Van Buskirk, Maia, Zoghbi, Sami S., Pike, Victor W., Innis, Robert B., Zanotti-Fregonara, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382351/
https://www.ncbi.nlm.nih.gov/pubmed/37249618
http://dx.doi.org/10.1007/s00259-023-06270-9