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Essential genes: a cross-species perspective
Protein coding genes exhibit different degrees of intolerance to loss-of-function variation. The most intolerant genes, whose function is essential for cell or/and organism survival, inform on fundamental biological processes related to cell proliferation and organism development and provide a windo...
Autores principales: | Cacheiro, Pilar, Smedley, Damian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382395/ https://www.ncbi.nlm.nih.gov/pubmed/36897351 http://dx.doi.org/10.1007/s00335-023-09984-1 |
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