Design of mirtazapine solid dispersion with different carriers’ systems: optimization, in vitro evaluation, and bioavailability assessment

The solid dispersion technique is the most effective and widely used approach for increasing the solubility and release of drugs that have low water solubility. Mirtazapine (MRT) is an atypical antidepressant used to treat severe depression. MRT has a low oral bioavailability (about 50%) due to its...

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Detalles Bibliográficos
Autores principales: Aldeeb, Reem Abd Elhameed, Mahdy, Mahmoud Abd El-Ghani, El-Nahas, Hanan Mohamed, Musallam, Abeer Abdelaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382405/
https://www.ncbi.nlm.nih.gov/pubmed/36940079
http://dx.doi.org/10.1007/s13346-023-01316-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382405/
https://www.ncbi.nlm.nih.gov/pubmed/36940079
http://dx.doi.org/10.1007/s13346-023-01316-9

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