Cargando…

Disruption of RCAN1.4 expression mediated by YY1/HDAC2 modulates chronic renal allograft interstitial fibrosis

Chronic allograft dysfunction (CAD) is a major factor that hinders kidney transplant survival in the long run. Epithelial–mesenchymal transition (EMT) has been confirmed to significantly contribute to interstitial fibrosis/tubular atrophy (IF/TA), which is the main histopathological feature of CAD....

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jianjian, Zhang, Yao, Feng, Dengyuan, Zhou, Hai, Gui, Zeping, Zheng, Ming, Hang, Zhou, Gu, Min, Tan, Ruoyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382480/ https://www.ncbi.nlm.nih.gov/pubmed/37507403 http://dx.doi.org/10.1038/s41420-023-01574-z

Ejemplares similares

RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2
por: Zhang, Jianjian, et al.
Publicado: (2021)

Macrophage polarization induces endothelium-to-myofibroblast transition in chronic allograft dysfunction
por: Gui, Zeping, et al.
Publicado: (2023)

Disruption of super-enhancer-driven tumor suppressor gene RCAN1.4 expression promotes the malignancy of breast carcinoma
por: Deng, Rong, et al.
Publicado: (2020)

Single Nucleotide Polymorphisms of IL-33 Gene Correlated with Renal Allograft Fibrosis in Kidney Transplant Recipients
por: Liu, Xuzhong, et al.
Publicado: (2021)

YY1 promotes HDAC1 expression and decreases sensitivity of hepatocellular carcinoma cells to HDAC inhibitor
por: Dong, Sheng, et al.
Publicado: (2017)

RCAN-11R peptide provides immunosuppression for fully mismatched islet allografts in mice
por: Noguchi, Hirofumi, et al.
Publicado: (2017)

Everolimus Alleviates Renal Allograft Interstitial Fibrosis by Inhibiting Epithelial-to-Mesenchymal Transition Not Only via Inducing Autophagy but Also via Stabilizing IκB-α
por: Gui, Zeping, et al.
Publicado: (2022)

RCAN1.4 suppresses the osteosarcoma growth and metastasis via interfering with the calcineurin/NFAT signaling pathway
por: Huang, Bao, et al.
Publicado: (2021)

Upregulation of RCAN1.4 by HIF1α alleviates OGD‐induced inflammatory response in astrocytes
por: Yang, Xiaxin, et al.
Publicado: (2022)

Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus
por: Cho, Kyung-Ok, et al.
Publicado: (2020)

The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs
por: Huang, Bao, et al.
Publicado: (2020)

RCAN1.4 mediates high glucose-induced matrix production by stimulating mitochondrial fission in mesangial cells
por: Chen, Hong-Min, et al.
Publicado: (2020)

A major role for RCAN1 in atherosclerosis progression
por: Méndez-Barbero, Nerea, et al.
Publicado: (2013)

Quercetin Induces Apoptosis in HepG2 Cells via Directly Interacting with YY1 to Disrupt YY1-p53 Interaction
por: Guan, Hui, et al.
Publicado: (2023)

Decreased activity of RCAN1.4 is a potential risk factor for congenital heart disease in a Han Chinese population
por: Cheng, Liangping, et al.
Publicado: (2018)

RCAN1-mediated calcineurin inhibition as a target for cancer therapy
por: Lao, Mengyi, et al.
Publicado: (2022)

RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells
por: Alghanem, Ahmad F., et al.
Publicado: (2017)

RCAN1C is differentially expressed in T helper cell subsets
por: Sieber, M, et al.
Publicado: (2009)

RCANs regulate the convergent roles of NFATc1 in bone homeostasis
por: Kim, Jung Ha, et al.
Publicado: (2016)

RCAN1 in the inverse association between Alzheimer’s disease and cancer
por: Fu, Qiang, et al.
Publicado: (2017)

OR09-2 The RCAN 1.4 Metastasis Progression Suppressor Gene is Hypermethylated at Intron 1 and Downregulated in Papillary Thyroid Cancer
por: Li, Wei, et al.
Publicado: (2022)

Histone deacetylase inhibitors inhibit lung adenocarcinoma metastasis via HDAC2/YY1 mediated downregulation of Cdh1
por: Wang, Dongmei, et al.
Publicado: (2023)

Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1
por: Dierssen, Mara, et al.
Publicado: (2011)

Histone Deacetylase 3 Promotes RCAN1 Stability and Nuclear Translocation
por: Han, Kyung Ah, et al.
Publicado: (2014)

RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis
por: Sun, Xiulian, et al.
Publicado: (2014)

Transcription factor YY1 inhibits the expression of THY1 to promote interstitial pulmonary fibrosis by activating the HSF1/miR-214 axis
por: Chen, Lin, et al.
Publicado: (2020)

Single Nucleotide Polymorphisms of Ubiquitin-Related Genes were Associated with Allograft Fibrosis of Renal Transplant Fibrosis
por: Gui, Zeping, et al.
Publicado: (2019)

Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1
por: Kim, Jeong Do, et al.
Publicado: (2007)

Dissecting the roles and clinical potential of YY1 in the tumor microenvironment
por: Li, MengNa, et al.
Publicado: (2023)

RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimer’s disease, and normative aging
por: Wong, Helen, et al.
Publicado: (2022)

Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development
por: Fang, Shaohai, et al.
Publicado: (2019)

RCAN1 Is an Important Mediator of Glucocorticoid-Induced Apoptosis in Human Leukemic Cells
por: Nagao, Kazuaki, et al.
Publicado: (2012)

The RCAN1 inhibits NF-κB and suppresses lymphoma growth in mice
por: Liu, C, et al.
Publicado: (2015)

The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin
por: Li, Yang, et al.
Publicado: (2020)

RCAN1 in cardiovascular diseases: molecular mechanisms and a potential therapeutic target
por: Wang, Shuai, et al.
Publicado: (2020)

Low RCAN1.2 mRNA Expression Is Associated with Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma
por: Yang, Haijun, et al.
Publicado: (2023)

YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway
por: Li, Wei, et al.
Publicado: (2022)

Genome-wide analysis of YY2 versus YY1 target genes
por: Chen, Li, et al.
Publicado: (2010)

CapsNetYY1: identifying YY1-mediated chromatin loops based on a capsule network architecture
por: Zhang, Zhimin, et al.
Publicado: (2023)

Disruption of YY1-EZH2 Interaction Using Synthetic Peptides Inhibits Breast Cancer Development
por: Yi, Cheng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gvm4k55jmekbc7g3dhojmndiol