The role of long non-coding RNA H19 in infertility

Infertility is defined as the failure to conceive after at least one year of unprotected intercourse. Long non-coding RNAs (lncRNAs) are transcripts that contain more than 200 nucleotides but do not convert into proteins. LncRNAs, particularly lncRNA H19, have been linked to the emergence and progre...

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Detalles Bibliográficos
Autores principales: Peng, Yuanyuan, Guo, Renhao, Shi, Bei, Li, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382492/
https://www.ncbi.nlm.nih.gov/pubmed/37507391
http://dx.doi.org/10.1038/s41420-023-01567-y
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author Peng, Yuanyuan
Guo, Renhao
Shi, Bei
Li, Da
author_facet Peng, Yuanyuan
Guo, Renhao
Shi, Bei
Li, Da
author_sort Peng, Yuanyuan
collection PubMed
description Infertility is defined as the failure to conceive after at least one year of unprotected intercourse. Long non-coding RNAs (lncRNAs) are transcripts that contain more than 200 nucleotides but do not convert into proteins. LncRNAs, particularly lncRNA H19, have been linked to the emergence and progression of various diseases. This review focuses on the role of H19 in infertility caused by polycystic ovary syndrome, endometriosis, uterine fibroids, diminished ovarian reserve, male factor, and assisted reproductive technology-related pathology, highlighting the potential of H19 as a molecular target for the future treatment of infertility.
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spelling pubmed-103824922023-07-30 The role of long non-coding RNA H19 in infertility Peng, Yuanyuan Guo, Renhao Shi, Bei Li, Da Cell Death Discov Review Article Infertility is defined as the failure to conceive after at least one year of unprotected intercourse. Long non-coding RNAs (lncRNAs) are transcripts that contain more than 200 nucleotides but do not convert into proteins. LncRNAs, particularly lncRNA H19, have been linked to the emergence and progression of various diseases. This review focuses on the role of H19 in infertility caused by polycystic ovary syndrome, endometriosis, uterine fibroids, diminished ovarian reserve, male factor, and assisted reproductive technology-related pathology, highlighting the potential of H19 as a molecular target for the future treatment of infertility. Nature Publishing Group UK 2023-07-28 /pmc/articles/PMC10382492/ /pubmed/37507391 http://dx.doi.org/10.1038/s41420-023-01567-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Peng, Yuanyuan
Guo, Renhao
Shi, Bei
Li, Da
The role of long non-coding RNA H19 in infertility
title The role of long non-coding RNA H19 in infertility
title_full The role of long non-coding RNA H19 in infertility
title_fullStr The role of long non-coding RNA H19 in infertility
title_full_unstemmed The role of long non-coding RNA H19 in infertility
title_short The role of long non-coding RNA H19 in infertility
title_sort role of long non-coding rna h19 in infertility
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382492/
https://www.ncbi.nlm.nih.gov/pubmed/37507391
http://dx.doi.org/10.1038/s41420-023-01567-y
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