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Techniques to produce and evaluate realistic multivariate synthetic data

Data modeling requires a sufficient sample size for reproducibility. A small sample size can inhibit model evaluation. A synthetic data generation technique addressing this small sample size problem is evaluated: from the space of arbitrarily distributed samples, a subgroup (class) has a latent mult...

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Autores principales: Heine, John, Fowler, Erin E. E., Berglund, Anders, Schell, Michael J., Eschrich, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382509/
https://www.ncbi.nlm.nih.gov/pubmed/37507387
http://dx.doi.org/10.1038/s41598-023-38832-0
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author Heine, John
Fowler, Erin E. E.
Berglund, Anders
Schell, Michael J.
Eschrich, Steven
author_facet Heine, John
Fowler, Erin E. E.
Berglund, Anders
Schell, Michael J.
Eschrich, Steven
author_sort Heine, John
collection PubMed
description Data modeling requires a sufficient sample size for reproducibility. A small sample size can inhibit model evaluation. A synthetic data generation technique addressing this small sample size problem is evaluated: from the space of arbitrarily distributed samples, a subgroup (class) has a latent multivariate normal characteristic; synthetic data can be generated from this class with univariate kernel density estimation (KDE); and synthetic samples are statistically like their respective samples. Three samples (n = 667) were investigated with 10 input variables (X). KDE was used to augment the sample size in X. Maps produced univariate normal variables in Y. Principal component analysis in Y produced uncorrelated variables in T, where the probability density functions were approximated as normal and characterized; synthetic data was generated with normally distributed univariate random variables in T. Reversing each step produced synthetic data in Y and X. All samples were approximately multivariate normal in Y, permitting the generation of synthetic data. Probability density function and covariance comparisons showed similarity between samples and synthetic samples. A class of samples has a latent normal characteristic. For such samples, this approach offers a solution to the small sample size problem. Further studies are required to understand this latent class.
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spelling pubmed-103825092023-07-30 Techniques to produce and evaluate realistic multivariate synthetic data Heine, John Fowler, Erin E. E. Berglund, Anders Schell, Michael J. Eschrich, Steven Sci Rep Article Data modeling requires a sufficient sample size for reproducibility. A small sample size can inhibit model evaluation. A synthetic data generation technique addressing this small sample size problem is evaluated: from the space of arbitrarily distributed samples, a subgroup (class) has a latent multivariate normal characteristic; synthetic data can be generated from this class with univariate kernel density estimation (KDE); and synthetic samples are statistically like their respective samples. Three samples (n = 667) were investigated with 10 input variables (X). KDE was used to augment the sample size in X. Maps produced univariate normal variables in Y. Principal component analysis in Y produced uncorrelated variables in T, where the probability density functions were approximated as normal and characterized; synthetic data was generated with normally distributed univariate random variables in T. Reversing each step produced synthetic data in Y and X. All samples were approximately multivariate normal in Y, permitting the generation of synthetic data. Probability density function and covariance comparisons showed similarity between samples and synthetic samples. A class of samples has a latent normal characteristic. For such samples, this approach offers a solution to the small sample size problem. Further studies are required to understand this latent class. Nature Publishing Group UK 2023-07-28 /pmc/articles/PMC10382509/ /pubmed/37507387 http://dx.doi.org/10.1038/s41598-023-38832-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Heine, John
Fowler, Erin E. E.
Berglund, Anders
Schell, Michael J.
Eschrich, Steven
Techniques to produce and evaluate realistic multivariate synthetic data
title Techniques to produce and evaluate realistic multivariate synthetic data
title_full Techniques to produce and evaluate realistic multivariate synthetic data
title_fullStr Techniques to produce and evaluate realistic multivariate synthetic data
title_full_unstemmed Techniques to produce and evaluate realistic multivariate synthetic data
title_short Techniques to produce and evaluate realistic multivariate synthetic data
title_sort techniques to produce and evaluate realistic multivariate synthetic data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382509/
https://www.ncbi.nlm.nih.gov/pubmed/37507387
http://dx.doi.org/10.1038/s41598-023-38832-0
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