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Techniques to produce and evaluate realistic multivariate synthetic data
Data modeling requires a sufficient sample size for reproducibility. A small sample size can inhibit model evaluation. A synthetic data generation technique addressing this small sample size problem is evaluated: from the space of arbitrarily distributed samples, a subgroup (class) has a latent mult...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382509/ https://www.ncbi.nlm.nih.gov/pubmed/37507387 http://dx.doi.org/10.1038/s41598-023-38832-0 |
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author | Heine, John Fowler, Erin E. E. Berglund, Anders Schell, Michael J. Eschrich, Steven |
author_facet | Heine, John Fowler, Erin E. E. Berglund, Anders Schell, Michael J. Eschrich, Steven |
author_sort | Heine, John |
collection | PubMed |
description | Data modeling requires a sufficient sample size for reproducibility. A small sample size can inhibit model evaluation. A synthetic data generation technique addressing this small sample size problem is evaluated: from the space of arbitrarily distributed samples, a subgroup (class) has a latent multivariate normal characteristic; synthetic data can be generated from this class with univariate kernel density estimation (KDE); and synthetic samples are statistically like their respective samples. Three samples (n = 667) were investigated with 10 input variables (X). KDE was used to augment the sample size in X. Maps produced univariate normal variables in Y. Principal component analysis in Y produced uncorrelated variables in T, where the probability density functions were approximated as normal and characterized; synthetic data was generated with normally distributed univariate random variables in T. Reversing each step produced synthetic data in Y and X. All samples were approximately multivariate normal in Y, permitting the generation of synthetic data. Probability density function and covariance comparisons showed similarity between samples and synthetic samples. A class of samples has a latent normal characteristic. For such samples, this approach offers a solution to the small sample size problem. Further studies are required to understand this latent class. |
format | Online Article Text |
id | pubmed-10382509 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-103825092023-07-30 Techniques to produce and evaluate realistic multivariate synthetic data Heine, John Fowler, Erin E. E. Berglund, Anders Schell, Michael J. Eschrich, Steven Sci Rep Article Data modeling requires a sufficient sample size for reproducibility. A small sample size can inhibit model evaluation. A synthetic data generation technique addressing this small sample size problem is evaluated: from the space of arbitrarily distributed samples, a subgroup (class) has a latent multivariate normal characteristic; synthetic data can be generated from this class with univariate kernel density estimation (KDE); and synthetic samples are statistically like their respective samples. Three samples (n = 667) were investigated with 10 input variables (X). KDE was used to augment the sample size in X. Maps produced univariate normal variables in Y. Principal component analysis in Y produced uncorrelated variables in T, where the probability density functions were approximated as normal and characterized; synthetic data was generated with normally distributed univariate random variables in T. Reversing each step produced synthetic data in Y and X. All samples were approximately multivariate normal in Y, permitting the generation of synthetic data. Probability density function and covariance comparisons showed similarity between samples and synthetic samples. A class of samples has a latent normal characteristic. For such samples, this approach offers a solution to the small sample size problem. Further studies are required to understand this latent class. Nature Publishing Group UK 2023-07-28 /pmc/articles/PMC10382509/ /pubmed/37507387 http://dx.doi.org/10.1038/s41598-023-38832-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Heine, John Fowler, Erin E. E. Berglund, Anders Schell, Michael J. Eschrich, Steven Techniques to produce and evaluate realistic multivariate synthetic data |
title | Techniques to produce and evaluate realistic multivariate synthetic data |
title_full | Techniques to produce and evaluate realistic multivariate synthetic data |
title_fullStr | Techniques to produce and evaluate realistic multivariate synthetic data |
title_full_unstemmed | Techniques to produce and evaluate realistic multivariate synthetic data |
title_short | Techniques to produce and evaluate realistic multivariate synthetic data |
title_sort | techniques to produce and evaluate realistic multivariate synthetic data |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382509/ https://www.ncbi.nlm.nih.gov/pubmed/37507387 http://dx.doi.org/10.1038/s41598-023-38832-0 |
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