Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells

The molecular programs that govern the directed differentiation of myeloid progenitor cells are still poorly defined. Using a previously established immortalized, phenotypically normal myeloid progenitor cell model mEB8-ER, we unveil a new mechanism mediated by STAT5 and STAT3 at a bifurcation point...

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Detalles Bibliográficos
Autores principales: Zhang, Meichao, Meng, Yiling, Ying, Yingxia, Zhou, Pingting, Zhang, Suning, Fang, Yong, Yao, Yuan, Li, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382539/
https://www.ncbi.nlm.nih.gov/pubmed/37507383
http://dx.doi.org/10.1038/s41420-023-01575-y

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