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Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

The inaccessibility of human cardiomyocytes significantly hindered years of cardiovascular research efforts. To overcome these limitations, non-human cell sources were used as proxies to study heart function and associated diseases. Rodent models became increasingly acceptable surrogates to model th...

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Detalles Bibliográficos
Autores principales: Bourque, Kyla, Jones-Tabah, Jace, Pétrin, Darlaine, Martin, Ryan D., Tanny, Jason C., Hébert, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382583/
https://www.ncbi.nlm.nih.gov/pubmed/37507481
http://dx.doi.org/10.1038/s41598-023-39525-4