Structural and functional fine mapping of cysteines in mammalian glutaredoxin reveal their differential oxidation susceptibility

Protein-S-glutathionylation is a post-translational modification involving the conjugation of glutathione to protein thiols, which can modulate the activity and structure of key cellular proteins. Glutaredoxins (GLRX) are oxidoreductases that regulate this process by performing deglutathionylation....

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Detalles Bibliográficos
Autores principales: Corteselli, Elizabeth M., Sharafi, Mona, Hondal, Robert, MacPherson, Maximilian, White, Sheryl, Lam, Ying-Wai, Gold, Clarissa, Manuel, Allison M., van der Vliet, Albert, Schneebeli, Severin T., Anathy, Vikas, Li, Jianing, Janssen-Heininger, Yvonne M. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382592/
https://www.ncbi.nlm.nih.gov/pubmed/37507364
http://dx.doi.org/10.1038/s41467-023-39664-2

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