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MicroRNA targeting: A novel therapeutic intervention for ovarian cancer
Ovarian cancer, a perilous form of cancer affecting the female reproductive system, exhibits intricate communication networks that contribute to its progression. This study aims to identify crucial molecular abnormalities linked to the disease to enhance diagnostic and therapeutic strategies. In par...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382632/ https://www.ncbi.nlm.nih.gov/pubmed/37521375 http://dx.doi.org/10.1016/j.bbrep.2023.101519 |
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author | Asl, Elmira Roshani Sarabandi, Sajed Shademan, Behrouz Dalvandi, Kourosh sheikhansari, Golshan Nourazarian, Alireza |
author_facet | Asl, Elmira Roshani Sarabandi, Sajed Shademan, Behrouz Dalvandi, Kourosh sheikhansari, Golshan Nourazarian, Alireza |
author_sort | Asl, Elmira Roshani |
collection | PubMed |
description | Ovarian cancer, a perilous form of cancer affecting the female reproductive system, exhibits intricate communication networks that contribute to its progression. This study aims to identify crucial molecular abnormalities linked to the disease to enhance diagnostic and therapeutic strategies. In particular, we investigate the role of microRNAs (miRNAs) as diagnostic biomarkers and explore their potential in treating ovarian cancer. By targeting miRNAs, which can influence multiple pathways and genes, substantial therapeutic benefits can be attained. In this review we want to shed light on the promising application of miRNA-based interventions and provide insights into the specific miRNAs implicated in ovarian cancer pathogenesis. |
format | Online Article Text |
id | pubmed-10382632 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-103826322023-07-30 MicroRNA targeting: A novel therapeutic intervention for ovarian cancer Asl, Elmira Roshani Sarabandi, Sajed Shademan, Behrouz Dalvandi, Kourosh sheikhansari, Golshan Nourazarian, Alireza Biochem Biophys Rep Review Article Ovarian cancer, a perilous form of cancer affecting the female reproductive system, exhibits intricate communication networks that contribute to its progression. This study aims to identify crucial molecular abnormalities linked to the disease to enhance diagnostic and therapeutic strategies. In particular, we investigate the role of microRNAs (miRNAs) as diagnostic biomarkers and explore their potential in treating ovarian cancer. By targeting miRNAs, which can influence multiple pathways and genes, substantial therapeutic benefits can be attained. In this review we want to shed light on the promising application of miRNA-based interventions and provide insights into the specific miRNAs implicated in ovarian cancer pathogenesis. Elsevier 2023-07-24 /pmc/articles/PMC10382632/ /pubmed/37521375 http://dx.doi.org/10.1016/j.bbrep.2023.101519 Text en © 2023 The Authors. Published by Elsevier B.V. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Article Asl, Elmira Roshani Sarabandi, Sajed Shademan, Behrouz Dalvandi, Kourosh sheikhansari, Golshan Nourazarian, Alireza MicroRNA targeting: A novel therapeutic intervention for ovarian cancer |
title | MicroRNA targeting: A novel therapeutic intervention for ovarian cancer |
title_full | MicroRNA targeting: A novel therapeutic intervention for ovarian cancer |
title_fullStr | MicroRNA targeting: A novel therapeutic intervention for ovarian cancer |
title_full_unstemmed | MicroRNA targeting: A novel therapeutic intervention for ovarian cancer |
title_short | MicroRNA targeting: A novel therapeutic intervention for ovarian cancer |
title_sort | microrna targeting: a novel therapeutic intervention for ovarian cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382632/ https://www.ncbi.nlm.nih.gov/pubmed/37521375 http://dx.doi.org/10.1016/j.bbrep.2023.101519 |
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