Role of Type I Interferon Signaling and Microglia in the Abnormal Long-term Potentiation and Object Place Recognition Deficits of Male Mice With a Mutation of the Tuberous Sclerosis 2 Gene

BACKGROUND: Tuberous sclerosis complex is a genetic disorder associated with high rates of intellectual disability and autism. Mice with a heterozygous null mutation of the Tsc2 gene (Tsc2(+/−)) show deficits in hippocampal-dependent tasks and abnormal long-term potentiation (LTP) in the hippocampal...

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Detalles Bibliográficos
Autores principales: López-Aranda, Manuel F., Boxx, Gayle M., Phan, Miranda, Bach, Karen, Mandanas, Rochelle, Herrera, Isaiah, Taloma, Sunrae, Thadani, Chirag, Lu, Odilia, Bui, Raymond, Liu, Shuhan, Li, Nan, Zhou, Yu, Cheng, Genhong, Silva, Alcino J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382699/
https://www.ncbi.nlm.nih.gov/pubmed/37519458
http://dx.doi.org/10.1016/j.bpsgos.2022.03.015

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