Dysfunction of cAMP–Protein Kinase A–Calcium Signaling Axis in Striatal Medium Spiny Neurons: A Role in Schizophrenia and Huntington’s Disease Neuropathology

BACKGROUND: Striatal medium spiny neurons (MSNs) are preferentially lost in Huntington’s disease. Genomic studies also implicate a direct role for MSNs in schizophrenia, a psychiatric disorder known to involve cortical neuron dysfunction. It remains unknown whether the two diseases share similar MSN...

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Detalles Bibliográficos
Autores principales: Fjodorova, Marija, Noakes, Zoe, De La Fuente, Daniel C., Errington, Adam C., Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382711/
https://www.ncbi.nlm.nih.gov/pubmed/37519464
http://dx.doi.org/10.1016/j.bpsgos.2022.03.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382711/
https://www.ncbi.nlm.nih.gov/pubmed/37519464
http://dx.doi.org/10.1016/j.bpsgos.2022.03.010

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