Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial

Background: African children with severe malaria are susceptible to Gram-negative bacterial co-infection, largely non-typhoidal Salmonellae, leading to a substantially higher rates of in-hospital and post-discharge mortality than those without bacteraemia. Current evidence for treating co-infection...

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Detalles Bibliográficos
Autores principales: Olupot-Olupot, Peter, Okiror, William, Mnjalla, Hellen, Muhindo, Rita, Uyoga, Sophie, Mpoya, Ayub, Williams, Thomas N, terHeine, Rob, Burger, David M, Urban, Britta, Connon, Roisin, George, Elizabeth C, Gibb, Diana M, Walker, A Sarah, Maitland, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382785/
https://www.ncbi.nlm.nih.gov/pubmed/37519413
http://dx.doi.org/10.12688/wellcomeopenres.16968.2

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