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Advancements in Inflammatory Bowel Disease: A Narrative Review of Diagnostics, Management, Epidemiology, Prevalence, Patient Outcomes, Quality of Life, and Clinical Presentation

Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is a chronic, immune-mediated disorder that impacts the gastrointestinal tract. Significant advancements in the diagnosis and treatment of IBD have been made during the past few decades, improving p...

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Autores principales: Muzammil, Muhammad Ali, Fariha, FNU, Patel, Tirath, Sohail, Rohab, Kumar, Munesh, Khan, Ejaz, Khanam, Bushra, Kumar, Satesh, Khatri, Mahima, Varrassi, Giustino, Vanga, Prasanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382792/
https://www.ncbi.nlm.nih.gov/pubmed/37519622
http://dx.doi.org/10.7759/cureus.41120
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author Muzammil, Muhammad Ali
Fariha, FNU
Patel, Tirath
Sohail, Rohab
Kumar, Munesh
Khan, Ejaz
Khanam, Bushra
Kumar, Satesh
Khatri, Mahima
Varrassi, Giustino
Vanga, Prasanthi
author_facet Muzammil, Muhammad Ali
Fariha, FNU
Patel, Tirath
Sohail, Rohab
Kumar, Munesh
Khan, Ejaz
Khanam, Bushra
Kumar, Satesh
Khatri, Mahima
Varrassi, Giustino
Vanga, Prasanthi
author_sort Muzammil, Muhammad Ali
collection PubMed
description Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is a chronic, immune-mediated disorder that impacts the gastrointestinal tract. Significant advancements in the diagnosis and treatment of IBD have been made during the past few decades, improving patient outcomes. This narrative review aims to provide an overview of recent developments in the diagnosis and treatment of IBD. Both from an evaluative and therapeutic standpoint, the management of IBD has undergone significant change. The standard of treatment for treating UC and CD patients has changed due to several medical developments. These developments include amino-salicylates, immunosuppressants, biological agents, and new therapeutics. The review also addresses the difficulties in applying these developments in clinical practice. Globally, the prevalence of IBD is rising, with Asia among the regions with the highest rates. These environments provide particular difficulties, such as poor disease knowledge, a lack of diagnostic services, and infectious IBD mimics. These issues must be resolved to diagnose and manage IBD in these populations accurately. New imaging modalities and other improvements in diagnostic methods have increased the precision and early identification of IBD. To reduce problems and improve patient outcomes, healthcare professionals treating patients with IBD must work effectively as a team. An extensive summary of current developments in the diagnosis and treatment of IBD is given in this narrative review. It draws attention to the therapeutic possibilities, difficulties, and uncertainties of integrating these developments into clinical practice. By keeping up with these changes, healthcare practitioners can better care for patients with IBD and improve their quality of life.
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spelling pubmed-103827922023-07-30 Advancements in Inflammatory Bowel Disease: A Narrative Review of Diagnostics, Management, Epidemiology, Prevalence, Patient Outcomes, Quality of Life, and Clinical Presentation Muzammil, Muhammad Ali Fariha, FNU Patel, Tirath Sohail, Rohab Kumar, Munesh Khan, Ejaz Khanam, Bushra Kumar, Satesh Khatri, Mahima Varrassi, Giustino Vanga, Prasanthi Cureus Family/General Practice Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is a chronic, immune-mediated disorder that impacts the gastrointestinal tract. Significant advancements in the diagnosis and treatment of IBD have been made during the past few decades, improving patient outcomes. This narrative review aims to provide an overview of recent developments in the diagnosis and treatment of IBD. Both from an evaluative and therapeutic standpoint, the management of IBD has undergone significant change. The standard of treatment for treating UC and CD patients has changed due to several medical developments. These developments include amino-salicylates, immunosuppressants, biological agents, and new therapeutics. The review also addresses the difficulties in applying these developments in clinical practice. Globally, the prevalence of IBD is rising, with Asia among the regions with the highest rates. These environments provide particular difficulties, such as poor disease knowledge, a lack of diagnostic services, and infectious IBD mimics. These issues must be resolved to diagnose and manage IBD in these populations accurately. New imaging modalities and other improvements in diagnostic methods have increased the precision and early identification of IBD. To reduce problems and improve patient outcomes, healthcare professionals treating patients with IBD must work effectively as a team. An extensive summary of current developments in the diagnosis and treatment of IBD is given in this narrative review. It draws attention to the therapeutic possibilities, difficulties, and uncertainties of integrating these developments into clinical practice. By keeping up with these changes, healthcare practitioners can better care for patients with IBD and improve their quality of life. Cureus 2023-06-28 /pmc/articles/PMC10382792/ /pubmed/37519622 http://dx.doi.org/10.7759/cureus.41120 Text en Copyright © 2023, Muzammil et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Muzammil, Muhammad Ali
Fariha, FNU
Patel, Tirath
Sohail, Rohab
Kumar, Munesh
Khan, Ejaz
Khanam, Bushra
Kumar, Satesh
Khatri, Mahima
Varrassi, Giustino
Vanga, Prasanthi
Advancements in Inflammatory Bowel Disease: A Narrative Review of Diagnostics, Management, Epidemiology, Prevalence, Patient Outcomes, Quality of Life, and Clinical Presentation
title Advancements in Inflammatory Bowel Disease: A Narrative Review of Diagnostics, Management, Epidemiology, Prevalence, Patient Outcomes, Quality of Life, and Clinical Presentation
title_full Advancements in Inflammatory Bowel Disease: A Narrative Review of Diagnostics, Management, Epidemiology, Prevalence, Patient Outcomes, Quality of Life, and Clinical Presentation
title_fullStr Advancements in Inflammatory Bowel Disease: A Narrative Review of Diagnostics, Management, Epidemiology, Prevalence, Patient Outcomes, Quality of Life, and Clinical Presentation
title_full_unstemmed Advancements in Inflammatory Bowel Disease: A Narrative Review of Diagnostics, Management, Epidemiology, Prevalence, Patient Outcomes, Quality of Life, and Clinical Presentation
title_short Advancements in Inflammatory Bowel Disease: A Narrative Review of Diagnostics, Management, Epidemiology, Prevalence, Patient Outcomes, Quality of Life, and Clinical Presentation
title_sort advancements in inflammatory bowel disease: a narrative review of diagnostics, management, epidemiology, prevalence, patient outcomes, quality of life, and clinical presentation
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382792/
https://www.ncbi.nlm.nih.gov/pubmed/37519622
http://dx.doi.org/10.7759/cureus.41120
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