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Biology-inspired graph neural network encodes reactome and reveals biochemical reactions of disease
Functional heterogeneity of healthy human tissues complicates interpretation of molecular studies, impeding precision therapeutic target identification and treatment. Considering this, we generated a graph neural network with Reactome-based architecture and trained it using 9,115 samples from Genoty...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382942/ https://www.ncbi.nlm.nih.gov/pubmed/37521042 http://dx.doi.org/10.1016/j.patter.2023.100758 |