Cargando…
Costs and Causes of Oncology Drug Attrition With the Example of Insulin-Like Growth Factor-1 Receptor Inhibitors
IMPORTANCE: The development of oncology drugs is expensive and beset by a high attrition rate. Analysis of the costs and causes of translational failure may help to reduce attrition and permit the more appropriate use of resources to reduce mortality from cancer. OBJECTIVE: To analyze the causes of...
Autores principales: | Jentzsch, Valerie, Osipenko, Leeza, Scannell, Jack W., Hickman, John A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383012/ https://www.ncbi.nlm.nih.gov/pubmed/37505498 http://dx.doi.org/10.1001/jamanetworkopen.2023.24977 |
Ejemplares similares
-
A new fetal RHD genotyping test: Costs and benefits of mass testing to target antenatal anti-D prophylaxis in England and Wales
por: Szczepura, Ala, et al.
Publicado: (2011) -
Provenance and Clinical Benefit of Medicines Introduced to the French Market, 2008 to 2018
por: Osipenko, Leeza, et al.
Publicado: (2023) -
Audit of data redaction practices in NICE technology appraisals from 1999 to 2019
por: Osipenko, Leeza
Publicado: (2021) -
Stage-Specific Plasticity in Ovary Size Is Regulated by Insulin/Insulin-Like Growth Factor and Ecdysone Signaling in Drosophila
por: Mendes, Cláudia C., et al.
Publicado: (2016) -
Genetic manipulation of insulin/insulin-like growth factor signaling pathway activity has sex-biased effects on Drosophila body size
por: Millington, Jason W, et al.
Publicado: (2021)