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Facilitation of Definitive Cancer Diagnosis With Quantitative Molecular Assays of BRAF V600E and TERT Promoter Variants in Patients With Thyroid Nodules

IMPORTANCE: Molecular testing of the presence of pathogenic genomic variants in a tumor without quantifying the variant allele fraction (VAF) does not differentiate the variation extent among tumors, often resulting in an inconclusive diagnosis because of interpatient variability. OBJECTIVE: To exam...

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Detalles Bibliográficos
Autores principales: Fu, Guodong, Chazen, Ronald S., Monteiro, Eric, Vescan, Allan, Freeman, Jeremy L., Witterick, Ian J., MacMillan, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383015/
https://www.ncbi.nlm.nih.gov/pubmed/37505499
http://dx.doi.org/10.1001/jamanetworkopen.2023.23500

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