Cargando…

Advances in saRNA Vaccine Research against Emerging/Re-Emerging Viruses

Although conventional vaccine approaches have proven to be successful in preventing infectious diseases in past decades, for vaccine development against emerging/re-emerging viruses, one of the main challenges is rapid response in terms of design and manufacture. mRNA vaccines can be designed and pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yalan, Li, Yuncheng, Hu, Qinxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383046/ https://www.ncbi.nlm.nih.gov/pubmed/37514957 http://dx.doi.org/10.3390/vaccines11071142

Ejemplares similares

Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer
por: Reebye, Vikash, et al.
Publicado: (2018)

The evaluation of novel oral vaccines based on self-amplifying RNA lipid nanparticles (saRNA LNPs), saRNA transfected Lactobacillus plantarum LNPs, and saRNA transfected Lactobacillus plantarum to neutralize SARS-CoV-2 variants alpha and delta
por: Keikha, Reza, et al.
Publicado: (2021)

Poly(2-oxazoline)/saRNA Polyplexes for Targeted and Nonviral Gene Delivery
por: Hayes, Graham, et al.
Publicado: (2023)

saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription
por: Portnoy, Victoria, et al.
Publicado: (2016)

Biophysical characterization of the structure of a SARS-CoV-2 self-amplifying RNA (saRNA) vaccine
por: Myatt, Daniel P, et al.
Publicado: (2023)

Therapeutic Potential of small Activating RNAs (saRNAs) in Human Cancers
por: Yoon, Sorah, et al.
Publicado: (2018)

AB224. SaRNA guided inos upregulation improves erectile function of diabetic rats
por: Wang, T, et al.
Publicado: (2014)

Targeted p53 activation by saRNA suppresses human bladder cancer cells growth and metastasis
por: Wang, Chenghe, et al.
Publicado: (2016)

Reactivation of HIC-1 gene by saRNA inhibits clonogenicity and invasiveness in breast cancer cells
por: ZHAO, FENG, et al.
Publicado: (2015)

Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA
por: Blakney, Anna K., et al.
Publicado: (2019)

Histone lysine methyltransferase-related neurodevelopmental disorders: current knowledge and saRNA future therapies
por: Roth, Charlotte, et al.
Publicado: (2023)

saRNA vaccine expressing membrane-anchored RBD elicits broad and durable immunity against SARS-CoV-2 variants of concern
por: Komori, Mai, et al.
Publicado: (2023)

Optimization of Lipid Nanoparticles for saRNA Expression and Cellular Activation Using a Design-of-Experiment Approach
por: Ly, Han Han, et al.
Publicado: (2022)

p21(CIP/WAF1) saRNA inhibits proliferative vitreoretinopathy in a rabbit model
por: Zhang, Qi, et al.
Publicado: (2023)

Big Is Beautiful: Enhanced saRNA Delivery and Immunogenicity by a Higher Molecular Weight, Bioreducible, Cationic Polymer
por: Blakney, Anna K., et al.
Publicado: (2020)

Targeted Delivery of C/EBPα-saRNA by RNA Aptamers Shows Anti-tumor Effects in a Mouse Model of Advanced PDAC
por: Yoon, Sorah, et al.
Publicado: (2019)

OX40 agonist stimulation increases and sustains humoral and cell-mediated responses to SARS-CoV-2 protein and saRNA vaccines
por: Duhen, Rebekka, et al.
Publicado: (2022)

A Mutation in Endogenous saRNA miR-23a Influences Granulosa Cells Response to Oxidative Stress
por: Wang, Siqi, et al.
Publicado: (2022)

Mechanism of Notch1-saRNA-1480 reversing androgen sensitivity in human metastatic castration-resistant prostate cancer
por: Ma, Libin, et al.
Publicado: (2020)

Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo
por: Yoon, Sorah, et al.
Publicado: (2016)

Migrasomes released by HSV-2-infected cells serve as a conveyance for virus spread
por: Liu, Yalan, et al.
Publicado: (2023)

Heterologous saRNA Prime, DNA Dual-Antigen Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies
por: Rice, Adrian, et al.
Publicado: (2022)

Human T-cell immunity against the emerging and re-emerging viruses
por: Zhao, Min, et al.
Publicado: (2017)

Current trends in designing antiviral agents against emerging and re-emerging RNA viruses
por: da Silva-Júnior, Edeildo F., et al.
Publicado: (2022)

Advances in Human Norovirus Vaccine Research
por: Zhang, Mudan, et al.
Publicado: (2021)

Sarna: una epidemia dentro de una pandemia
por: Casals, Miquel
Publicado: (2021)

Emerging and re-emerging porcine viruses
por: Meng, Xiang-Jin, et al.
Publicado: (2020)

Editorial: Evolution & Genomic Adaptation of Emerging and Re-emerging RNA Viruses
por: Huang, Kai, et al.
Publicado: (2021)

Third Tofo Advanced Study Week on Emerging and Re-emerging Viruses, 2018
por: Badolo, Athanase, et al.
Publicado: (2019)

PPFIA1-targeting miR-181a mimic and saRNA overcome imatinib resistance in BCR-ABL1-independent chronic myeloid leukemia by suppressing leukemia stem cell regeneration
por: Su, Rui, et al.
Publicado: (2023)

Utility of Proteomics in Emerging and Re-Emerging Infectious Diseases Caused by RNA Viruses
por: Sperk, Maike, et al.
Publicado: (2020)

Patent intelligence of RNA viruses: Implications for combating emerging and re-emerging RNA virus based infectious diseases
por: Devarapalli, Pratap, et al.
Publicado: (2022)

The Re-Emergence of Hepatitis E Virus in Europe and Vaccine Development
por: Zahmanova, Gergana, et al.
Publicado: (2023)

Human Norovirus NTPase Antagonizes Interferon-β Production by Interacting With IkB Kinase ε
por: Zheng, Zifeng, et al.
Publicado: (2021)

Receptor-binding domains of spike proteins of emerging or re-emerging viruses as targets for development of antiviral vaccines
por: Jiang, Shibo, et al.
Publicado: (2012)

Emerging and re-emerging viruses affecting the nervous system
por: Meyding-Lamadé, Uta, et al.
Publicado: (2019)

Emerging and re-emerging viruses in Malaysia, 1997–2007
por: Tee, Kok Keng, et al.
Publicado: (2009)

Hylin-a1: A Pan-Inhibitor against Emerging and Re-Emerging Respiratory Viruses
por: Chianese, Annalisa, et al.
Publicado: (2023)

Chimeric Japanese Encephalitis Virus SA14/SA14-14-2 Was Virulence Attenuated and Protected the Challenge of Wild-Type Strain SA14
por: Huang, Rong, et al.
Publicado: (2019)

Mechanisms of innate immune evasion in re-emerging RNA viruses
por: Ma, Daphne Y, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qkv4c0n2crutsqdcr55bpfuk9k