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Hepatitis C Virus Down-Regulates the Expression of Ribonucleotide Reductases to Promote Its Replication

Ribonucleotide reductases (RRs or RNRs) catalyze the reduction of the OH group on the 2nd carbon of ribose, reducing four ribonucleotides (NTPs) to the corresponding deoxyribonucleotides (dNTPs) to promote DNA synthesis. Large DNA viruses, such as herpesviruses and poxviruses, could benefit their re...

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Detalles Bibliográficos
Autores principales: Yang, Chee-Hing, Wu, Cheng-Hao, Lo, Shih-Yen, Lua, Ahai-Chang, Chan, Yu-Ru, Li, Hui-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383090/
https://www.ncbi.nlm.nih.gov/pubmed/37513740
http://dx.doi.org/10.3390/pathogens12070892