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Hepatitis C Virus Down-Regulates the Expression of Ribonucleotide Reductases to Promote Its Replication
Ribonucleotide reductases (RRs or RNRs) catalyze the reduction of the OH group on the 2nd carbon of ribose, reducing four ribonucleotides (NTPs) to the corresponding deoxyribonucleotides (dNTPs) to promote DNA synthesis. Large DNA viruses, such as herpesviruses and poxviruses, could benefit their re...
Autores principales: | Yang, Chee-Hing, Wu, Cheng-Hao, Lo, Shih-Yen, Lua, Ahai-Chang, Chan, Yu-Ru, Li, Hui-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383090/ https://www.ncbi.nlm.nih.gov/pubmed/37513740 http://dx.doi.org/10.3390/pathogens12070892 |
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