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The Over-Irradiation Metabolite Derivative, 24-Hydroxylumister-ol(3), Reduces UV-Induced Damage in Skin
The hormonal form of vitamin D(3), 1,25(OH)(2)D(3), reduces UV-induced DNA damage. UV exposure initiates pre-vitamin D(3) production in the skin, and continued UV exposure photoisomerizes pre-vitamin D(3) to produce “over-irradiation products” such as lumisterol(3) (L(3)). Cytochrome P450 side-chain...
Autores principales: | De Silva, Warusavithana Gunawardena Manori, McCarthy, Bianca Yuko, Han, Jeremy, Yang, Chen, Holland, Andrew J. A., Stern, Harvey, Dixon, Katie Marie, Tang, Edith Kai Yan, Tuckey, Robert Charles, Rybchyn, Mark Stephen, Mason, Rebecca Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383208/ https://www.ncbi.nlm.nih.gov/pubmed/37512482 http://dx.doi.org/10.3390/metabo13070775 |
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