Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N-Acylhydrazone Derivatives of Pyrrolo[3,4-d]pyridazinone as Dual COX/LOX Inhibitors

Secure and efficient treatment of diverse pain and inflammatory disorders is continually challenging. Although NSAIDs and other painkillers are well-known and commonly available, they are sometimes insufficient and can cause dangerous adverse effects. As yet reported, derivatives of pyrrolo[3,4-d]py...

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Detalles Bibliográficos
Autores principales: Mikus, Jakub, Świątek, Piotr, Przybyła, Patrycja, Krzyżak, Edward, Marciniak, Aleksandra, Kotynia, Aleksadra, Redzicka, Aleksandra, Wiatrak, Benita, Jawień, Paulina, Gębarowski, Tomasz, Szczukowski, Łukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383271/
https://www.ncbi.nlm.nih.gov/pubmed/37513351
http://dx.doi.org/10.3390/molecules28145479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383271/
https://www.ncbi.nlm.nih.gov/pubmed/37513351
http://dx.doi.org/10.3390/molecules28145479

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