The Expression of Stem Cell Marker LGR5 and Its Coexpression with Β-Catenin in Sporadic Colorectal Carcinoma and Adenoma: A Comparative Immunohistochemical Study

Background: LGR5 is one of the most important stem cell markers for colorectal cancer (CRC), as it potentiates Wnt/Β-catenin signaling. The well-characterized deregulation of Wnt/Β-catenin signaling that occurs during adenoma/carcinoma sequence in CRC renders LGR5 a hopeful therapeutic target. We as...

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Detalles Bibliográficos
Autores principales: Ahmed, Eman Mohamed, Farag, Abeer Said, Abdelwahed, Mohammed S., Hanbazazh, Mehenaz, Samman, Abdulhadi, Ashmawy, Diaa, Abd-Elhameed, Nageh Rady, Tharwat, Mohamed, Othman, Alyaa E., Shawky, Taiseer Ahmed, Attia, Radwa Mohamed, Ibrahim, Adel Abdelwahid, Azzam, Sherif, Elhussiny, Mohammed E. A., Nasr, Mohamed, Naeem, Suhaib Alsayed, Abd-Elhay, Wagih M., Alfaifi, Ahmed Mohammad Ali, Hasan, Abdulkarim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383310/
https://www.ncbi.nlm.nih.gov/pubmed/37512045
http://dx.doi.org/10.3390/medicina59071233

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