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Comparison of Microwave Hyperthermia Applicator Designs with Fora Dipole and Connected Array

In microwave hyperthermia tumor therapy, electromagnetic waves focus energy on the tumor to elevate the temperature above its normal levels with minimal injury to the surrounding healthy tissue. Microwave hyperthermia applicator design is important for the effectiveness of the therapy and the feasib...

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Autores principales: Yildiz, Gulsah, Farhat, Iman, Farrugia, Lourdes, Bonello, Julian, Zarb-Adami, Kristian, Sammut, Charles V., Yilmaz, Tuba, Akduman, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383607/
https://www.ncbi.nlm.nih.gov/pubmed/37514884
http://dx.doi.org/10.3390/s23146592
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author Yildiz, Gulsah
Farhat, Iman
Farrugia, Lourdes
Bonello, Julian
Zarb-Adami, Kristian
Sammut, Charles V.
Yilmaz, Tuba
Akduman, Ibrahim
author_facet Yildiz, Gulsah
Farhat, Iman
Farrugia, Lourdes
Bonello, Julian
Zarb-Adami, Kristian
Sammut, Charles V.
Yilmaz, Tuba
Akduman, Ibrahim
author_sort Yildiz, Gulsah
collection PubMed
description In microwave hyperthermia tumor therapy, electromagnetic waves focus energy on the tumor to elevate the temperature above its normal levels with minimal injury to the surrounding healthy tissue. Microwave hyperthermia applicator design is important for the effectiveness of the therapy and the feasibility of real-time application. In this study, the potential of using fractal octagonal ring antenna elements as a dipole antenna array and as a connected array at 2.45 GHz for breast tumor hyperthermia application was investigated. Microwave hyperthermia treatment models consisting of different fractal octagonal ring antenna array designs and a breast phantom are simulated in COMSOL Multiphysics to obtain the field distributions. The antenna excitation phases and magnitudes are optimized using the global particle swarm algorithm to selectively increase the specific absorption rate at the target region while minimizing hot spots in other regions within the breast. Specific absorption rate distributions, obtained inside the phantom, are analyzed for each proposed microwave hyperthermia applicator design. The dipole fractal octagonal ring antenna arrays are comparatively assessed for three different designs: circular, linear, and Cross—array. The 16-antenna dipole array performance was superior for all three 1-layer applicator designs, and no distinct difference was found between 16-antenna circular, linear, or cross arrays. Two-layer dipole arrays have better performance in the deep-tissue targets than one-layer arrays. The performance of the connected array with a higher number of layers exceeds the performance of the dipole arrays in the superficial regions, while they are comparable for deep regions of the breast. The 1-layer 12-antenna circular FORA dipole array feasibility as a microwave hyperthermia applicator was experimentally shown.
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spelling pubmed-103836072023-07-30 Comparison of Microwave Hyperthermia Applicator Designs with Fora Dipole and Connected Array Yildiz, Gulsah Farhat, Iman Farrugia, Lourdes Bonello, Julian Zarb-Adami, Kristian Sammut, Charles V. Yilmaz, Tuba Akduman, Ibrahim Sensors (Basel) Article In microwave hyperthermia tumor therapy, electromagnetic waves focus energy on the tumor to elevate the temperature above its normal levels with minimal injury to the surrounding healthy tissue. Microwave hyperthermia applicator design is important for the effectiveness of the therapy and the feasibility of real-time application. In this study, the potential of using fractal octagonal ring antenna elements as a dipole antenna array and as a connected array at 2.45 GHz for breast tumor hyperthermia application was investigated. Microwave hyperthermia treatment models consisting of different fractal octagonal ring antenna array designs and a breast phantom are simulated in COMSOL Multiphysics to obtain the field distributions. The antenna excitation phases and magnitudes are optimized using the global particle swarm algorithm to selectively increase the specific absorption rate at the target region while minimizing hot spots in other regions within the breast. Specific absorption rate distributions, obtained inside the phantom, are analyzed for each proposed microwave hyperthermia applicator design. The dipole fractal octagonal ring antenna arrays are comparatively assessed for three different designs: circular, linear, and Cross—array. The 16-antenna dipole array performance was superior for all three 1-layer applicator designs, and no distinct difference was found between 16-antenna circular, linear, or cross arrays. Two-layer dipole arrays have better performance in the deep-tissue targets than one-layer arrays. The performance of the connected array with a higher number of layers exceeds the performance of the dipole arrays in the superficial regions, while they are comparable for deep regions of the breast. The 1-layer 12-antenna circular FORA dipole array feasibility as a microwave hyperthermia applicator was experimentally shown. MDPI 2023-07-21 /pmc/articles/PMC10383607/ /pubmed/37514884 http://dx.doi.org/10.3390/s23146592 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yildiz, Gulsah
Farhat, Iman
Farrugia, Lourdes
Bonello, Julian
Zarb-Adami, Kristian
Sammut, Charles V.
Yilmaz, Tuba
Akduman, Ibrahim
Comparison of Microwave Hyperthermia Applicator Designs with Fora Dipole and Connected Array
title Comparison of Microwave Hyperthermia Applicator Designs with Fora Dipole and Connected Array
title_full Comparison of Microwave Hyperthermia Applicator Designs with Fora Dipole and Connected Array
title_fullStr Comparison of Microwave Hyperthermia Applicator Designs with Fora Dipole and Connected Array
title_full_unstemmed Comparison of Microwave Hyperthermia Applicator Designs with Fora Dipole and Connected Array
title_short Comparison of Microwave Hyperthermia Applicator Designs with Fora Dipole and Connected Array
title_sort comparison of microwave hyperthermia applicator designs with fora dipole and connected array
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383607/
https://www.ncbi.nlm.nih.gov/pubmed/37514884
http://dx.doi.org/10.3390/s23146592
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