MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II

MSN8C, an analog of mansonone E, has been identified as a novel catalytic inhibitor of human DNA topoisomerase II that induces tumor regression and differs from VP-16(etoposide). Treatment with MSN8C showed significant antiproliferative activity against eleven human tumor cell lines in vitro. It was...

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Detalles Bibliográficos
Autores principales: Ou, Jie-Bin, Huang, Wei-Hao, Liu, Xing-Zi, Dai, Guo-Yao, Wang, Lu, Huang, Zhi-Shu, Huang, Shi-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383749/
https://www.ncbi.nlm.nih.gov/pubmed/37513470
http://dx.doi.org/10.3390/molecules28145598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383749/
https://www.ncbi.nlm.nih.gov/pubmed/37513470
http://dx.doi.org/10.3390/molecules28145598

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