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MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II

MSN8C, an analog of mansonone E, has been identified as a novel catalytic inhibitor of human DNA topoisomerase II that induces tumor regression and differs from VP-16(etoposide). Treatment with MSN8C showed significant antiproliferative activity against eleven human tumor cell lines in vitro. It was...

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Detalles Bibliográficos
Autores principales:	Ou, Jie-Bin, Huang, Wei-Hao, Liu, Xing-Zi, Dai, Guo-Yao, Wang, Lu, Huang, Zhi-Shu, Huang, Shi-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383749/ https://www.ncbi.nlm.nih.gov/pubmed/37513470 http://dx.doi.org/10.3390/molecules28145598

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