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Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations

Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of semi-solid prodrug nanoparticle (SSPN) LAI formulations of emtricitabine (FTC) is reported here. Pharmacokinetics over 28 days were assessed i...

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Detalles Bibliográficos
Autores principales: Curley, Paul, Hobson, James J., Liptrott, Neill J., Makarov, Edward, Al-khouja, Amer, Tatham, Lee, David, Christopher A. W., Box, Helen, Neary, Megan, Sharp, Joanne, Pertinez, Henry, Meyers, David, Flexner, Charles, Freel Meyers, Caren L., Poluektova, Larisa, Rannard, Steve, Owen, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383755/
https://www.ncbi.nlm.nih.gov/pubmed/37514020
http://dx.doi.org/10.3390/pharmaceutics15071835

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