Cargando…

Probiotics, the Immune Response and Acute Appendicitis: A Review

Acute appendicitis is a common reason for admission to the Emergency Department (ED). It affects almost 70% of people under 30 years of age and 10% over 60 years of age. Its diagnosis includes the combination of clinical signs, laboratory tests and imaging. For years, surgical appendectomy has been...

Descripción completa

Detalles Bibliográficos
Autores principales: Petruzziello, Carmine, Saviano, Angela, Ojetti, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383843/
https://www.ncbi.nlm.nih.gov/pubmed/37514986
http://dx.doi.org/10.3390/vaccines11071170
_version_ 1785081010571968512
author Petruzziello, Carmine
Saviano, Angela
Ojetti, Veronica
author_facet Petruzziello, Carmine
Saviano, Angela
Ojetti, Veronica
author_sort Petruzziello, Carmine
collection PubMed
description Acute appendicitis is a common reason for admission to the Emergency Department (ED). It affects almost 70% of people under 30 years of age and 10% over 60 years of age. Its diagnosis includes the combination of clinical signs, laboratory tests and imaging. For years, surgical appendectomy has been the first-line therapy for acute appendicitis, but currently the management has shown some changes, in particular in patients with uncomplicated appendicitis. Recent studies have investigated the use of probiotics as an adjunctive therapy with promising results in conferring health benefits to patients with acute appendicitis. The aim of our review is to summarize the results of clinical studies about probiotics and the immunological response in acute appendicitis, discussing the limitations and future directions of this research.
format Online
Article
Text
id pubmed-10383843
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-103838432023-07-30 Probiotics, the Immune Response and Acute Appendicitis: A Review Petruzziello, Carmine Saviano, Angela Ojetti, Veronica Vaccines (Basel) Review Acute appendicitis is a common reason for admission to the Emergency Department (ED). It affects almost 70% of people under 30 years of age and 10% over 60 years of age. Its diagnosis includes the combination of clinical signs, laboratory tests and imaging. For years, surgical appendectomy has been the first-line therapy for acute appendicitis, but currently the management has shown some changes, in particular in patients with uncomplicated appendicitis. Recent studies have investigated the use of probiotics as an adjunctive therapy with promising results in conferring health benefits to patients with acute appendicitis. The aim of our review is to summarize the results of clinical studies about probiotics and the immunological response in acute appendicitis, discussing the limitations and future directions of this research. MDPI 2023-06-28 /pmc/articles/PMC10383843/ /pubmed/37514986 http://dx.doi.org/10.3390/vaccines11071170 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Petruzziello, Carmine
Saviano, Angela
Ojetti, Veronica
Probiotics, the Immune Response and Acute Appendicitis: A Review
title Probiotics, the Immune Response and Acute Appendicitis: A Review
title_full Probiotics, the Immune Response and Acute Appendicitis: A Review
title_fullStr Probiotics, the Immune Response and Acute Appendicitis: A Review
title_full_unstemmed Probiotics, the Immune Response and Acute Appendicitis: A Review
title_short Probiotics, the Immune Response and Acute Appendicitis: A Review
title_sort probiotics, the immune response and acute appendicitis: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383843/
https://www.ncbi.nlm.nih.gov/pubmed/37514986
http://dx.doi.org/10.3390/vaccines11071170
work_keys_str_mv AT petruzziellocarmine probioticstheimmuneresponseandacuteappendicitisareview
AT savianoangela probioticstheimmuneresponseandacuteappendicitisareview
AT ojettiveronica probioticstheimmuneresponseandacuteappendicitisareview