Cargando…
Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid
The inhalation of natural nanoparticles (NPs) emitted from volcanic activity may be a risk to human health. However, the literature rarely reports the fate and response of NPs once in contact with lung fluids. In this work, we studied the particle size distribution of ashfall from Popocatépetl volca...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383943/ https://www.ncbi.nlm.nih.gov/pubmed/37505589 http://dx.doi.org/10.3390/toxics11070624 |
_version_ | 1785081035550097408 |
---|---|
author | Schiavo, Benedetto Morton-Bermea, Ofelia Meza-Figueroa, Diana Acosta-Elías, Mónica González-Grijalva, Belem Armienta-Hernández, Maria Aurora Inguaggiato, Claudio Valera-Fernández, Daisy |
author_facet | Schiavo, Benedetto Morton-Bermea, Ofelia Meza-Figueroa, Diana Acosta-Elías, Mónica González-Grijalva, Belem Armienta-Hernández, Maria Aurora Inguaggiato, Claudio Valera-Fernández, Daisy |
author_sort | Schiavo, Benedetto |
collection | PubMed |
description | The inhalation of natural nanoparticles (NPs) emitted from volcanic activity may be a risk to human health. However, the literature rarely reports the fate and response of NPs once in contact with lung fluids. In this work, we studied the particle size distribution of ashfall from Popocatépetl volcano, Mexico. The collected ashes (n = 5) were analyzed with scanning electron microscopy (SEM) to obtain the elemental composition and morphology, and to determine the size of the ash particles using ParticleMetric software (PMS). The PMS reported most of the ash to have submicrometric size (<1 μm) and an average equivalent circle of 2.72 μm. Moreover, to our knowledge, this study investigated for the first time the behavior of ash NPs at different times (0 to 24 h) while in contact with in vitro lung fluid, Gamble Solution (GS) and Artificial Lysosomal Fluid (ALF) using dynamic light scattering (DLS). We found a large variability in the hydrodynamic diameter, with values less than 1 nm and greater than 5 μm. Furthermore, aggregation and disaggregation processes were recognized in GS and ALF, respectively. The results of this study increase the knowledge of the interaction between NPs and lung fluids, particularly within the alveolar macrophage region. |
format | Online Article Text |
id | pubmed-10383943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103839432023-07-30 Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid Schiavo, Benedetto Morton-Bermea, Ofelia Meza-Figueroa, Diana Acosta-Elías, Mónica González-Grijalva, Belem Armienta-Hernández, Maria Aurora Inguaggiato, Claudio Valera-Fernández, Daisy Toxics Article The inhalation of natural nanoparticles (NPs) emitted from volcanic activity may be a risk to human health. However, the literature rarely reports the fate and response of NPs once in contact with lung fluids. In this work, we studied the particle size distribution of ashfall from Popocatépetl volcano, Mexico. The collected ashes (n = 5) were analyzed with scanning electron microscopy (SEM) to obtain the elemental composition and morphology, and to determine the size of the ash particles using ParticleMetric software (PMS). The PMS reported most of the ash to have submicrometric size (<1 μm) and an average equivalent circle of 2.72 μm. Moreover, to our knowledge, this study investigated for the first time the behavior of ash NPs at different times (0 to 24 h) while in contact with in vitro lung fluid, Gamble Solution (GS) and Artificial Lysosomal Fluid (ALF) using dynamic light scattering (DLS). We found a large variability in the hydrodynamic diameter, with values less than 1 nm and greater than 5 μm. Furthermore, aggregation and disaggregation processes were recognized in GS and ALF, respectively. The results of this study increase the knowledge of the interaction between NPs and lung fluids, particularly within the alveolar macrophage region. MDPI 2023-07-19 /pmc/articles/PMC10383943/ /pubmed/37505589 http://dx.doi.org/10.3390/toxics11070624 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Schiavo, Benedetto Morton-Bermea, Ofelia Meza-Figueroa, Diana Acosta-Elías, Mónica González-Grijalva, Belem Armienta-Hernández, Maria Aurora Inguaggiato, Claudio Valera-Fernández, Daisy Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid |
title | Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid |
title_full | Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid |
title_fullStr | Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid |
title_full_unstemmed | Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid |
title_short | Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid |
title_sort | characterization and polydispersity of volcanic ash nanoparticles in synthetic lung fluid |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383943/ https://www.ncbi.nlm.nih.gov/pubmed/37505589 http://dx.doi.org/10.3390/toxics11070624 |
work_keys_str_mv | AT schiavobenedetto characterizationandpolydispersityofvolcanicashnanoparticlesinsyntheticlungfluid AT mortonbermeaofelia characterizationandpolydispersityofvolcanicashnanoparticlesinsyntheticlungfluid AT mezafigueroadiana characterizationandpolydispersityofvolcanicashnanoparticlesinsyntheticlungfluid AT acostaeliasmonica characterizationandpolydispersityofvolcanicashnanoparticlesinsyntheticlungfluid AT gonzalezgrijalvabelem characterizationandpolydispersityofvolcanicashnanoparticlesinsyntheticlungfluid AT armientahernandezmariaaurora characterizationandpolydispersityofvolcanicashnanoparticlesinsyntheticlungfluid AT inguaggiatoclaudio characterizationandpolydispersityofvolcanicashnanoparticlesinsyntheticlungfluid AT valerafernandezdaisy characterizationandpolydispersityofvolcanicashnanoparticlesinsyntheticlungfluid |