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Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid

The inhalation of natural nanoparticles (NPs) emitted from volcanic activity may be a risk to human health. However, the literature rarely reports the fate and response of NPs once in contact with lung fluids. In this work, we studied the particle size distribution of ashfall from Popocatépetl volca...

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Autores principales: Schiavo, Benedetto, Morton-Bermea, Ofelia, Meza-Figueroa, Diana, Acosta-Elías, Mónica, González-Grijalva, Belem, Armienta-Hernández, Maria Aurora, Inguaggiato, Claudio, Valera-Fernández, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383943/
https://www.ncbi.nlm.nih.gov/pubmed/37505589
http://dx.doi.org/10.3390/toxics11070624
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author Schiavo, Benedetto
Morton-Bermea, Ofelia
Meza-Figueroa, Diana
Acosta-Elías, Mónica
González-Grijalva, Belem
Armienta-Hernández, Maria Aurora
Inguaggiato, Claudio
Valera-Fernández, Daisy
author_facet Schiavo, Benedetto
Morton-Bermea, Ofelia
Meza-Figueroa, Diana
Acosta-Elías, Mónica
González-Grijalva, Belem
Armienta-Hernández, Maria Aurora
Inguaggiato, Claudio
Valera-Fernández, Daisy
author_sort Schiavo, Benedetto
collection PubMed
description The inhalation of natural nanoparticles (NPs) emitted from volcanic activity may be a risk to human health. However, the literature rarely reports the fate and response of NPs once in contact with lung fluids. In this work, we studied the particle size distribution of ashfall from Popocatépetl volcano, Mexico. The collected ashes (n = 5) were analyzed with scanning electron microscopy (SEM) to obtain the elemental composition and morphology, and to determine the size of the ash particles using ParticleMetric software (PMS). The PMS reported most of the ash to have submicrometric size (<1 μm) and an average equivalent circle of 2.72 μm. Moreover, to our knowledge, this study investigated for the first time the behavior of ash NPs at different times (0 to 24 h) while in contact with in vitro lung fluid, Gamble Solution (GS) and Artificial Lysosomal Fluid (ALF) using dynamic light scattering (DLS). We found a large variability in the hydrodynamic diameter, with values less than 1 nm and greater than 5 μm. Furthermore, aggregation and disaggregation processes were recognized in GS and ALF, respectively. The results of this study increase the knowledge of the interaction between NPs and lung fluids, particularly within the alveolar macrophage region.
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spelling pubmed-103839432023-07-30 Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid Schiavo, Benedetto Morton-Bermea, Ofelia Meza-Figueroa, Diana Acosta-Elías, Mónica González-Grijalva, Belem Armienta-Hernández, Maria Aurora Inguaggiato, Claudio Valera-Fernández, Daisy Toxics Article The inhalation of natural nanoparticles (NPs) emitted from volcanic activity may be a risk to human health. However, the literature rarely reports the fate and response of NPs once in contact with lung fluids. In this work, we studied the particle size distribution of ashfall from Popocatépetl volcano, Mexico. The collected ashes (n = 5) were analyzed with scanning electron microscopy (SEM) to obtain the elemental composition and morphology, and to determine the size of the ash particles using ParticleMetric software (PMS). The PMS reported most of the ash to have submicrometric size (<1 μm) and an average equivalent circle of 2.72 μm. Moreover, to our knowledge, this study investigated for the first time the behavior of ash NPs at different times (0 to 24 h) while in contact with in vitro lung fluid, Gamble Solution (GS) and Artificial Lysosomal Fluid (ALF) using dynamic light scattering (DLS). We found a large variability in the hydrodynamic diameter, with values less than 1 nm and greater than 5 μm. Furthermore, aggregation and disaggregation processes were recognized in GS and ALF, respectively. The results of this study increase the knowledge of the interaction between NPs and lung fluids, particularly within the alveolar macrophage region. MDPI 2023-07-19 /pmc/articles/PMC10383943/ /pubmed/37505589 http://dx.doi.org/10.3390/toxics11070624 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Schiavo, Benedetto
Morton-Bermea, Ofelia
Meza-Figueroa, Diana
Acosta-Elías, Mónica
González-Grijalva, Belem
Armienta-Hernández, Maria Aurora
Inguaggiato, Claudio
Valera-Fernández, Daisy
Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid
title Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid
title_full Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid
title_fullStr Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid
title_full_unstemmed Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid
title_short Characterization and Polydispersity of Volcanic Ash Nanoparticles in Synthetic Lung Fluid
title_sort characterization and polydispersity of volcanic ash nanoparticles in synthetic lung fluid
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383943/
https://www.ncbi.nlm.nih.gov/pubmed/37505589
http://dx.doi.org/10.3390/toxics11070624
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