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Enhanced Systemic Humoral Immune Response Induced in Mice by Generalized Modules for Membrane Antigens (GMMA) Is Associated with Affinity Maturation and Isotype Switching
Generalized Modules for Membrane Antigens (GMMA) are outer membrane vesicles derived from Gram-negative bacteria that can be used to design affordable subunit vaccines. GMMA have been observed to induce a potent humoral immune response in preclinical and clinical studies. In addition, in preclinical...
Autores principales: | Piccioli, Diego, Buricchi, Francesca, Bacconi, Marta, Bechi, Nicoletta, Galli, Barbara, Ferlicca, Francesca, Luzzi, Enrico, Cartocci, Elena, Marchi, Sara, Romagnoli, Giacomo, Alfini, Renzo, Di Benedetto, Roberta, Gallorini, Simona, Savino, Silvana, Brunelli, Brunella, Bartolini, Erika, Micoli, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384117/ https://www.ncbi.nlm.nih.gov/pubmed/37515035 http://dx.doi.org/10.3390/vaccines11071219 |
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