Dissecting the Role of SMYD2 and Its Inhibitor (LLY-507) in the Treatment of Chemically Induced Non-Small Cell Lung Cancer (NSCLC) by Using Fe(3)O(4) Nanoparticles Drug Delivery System

Cancer therapies based on nanoparticles with a loaded drug can overcome the problem of the drug’s toxic effects in the traditional chemotherapeutic approach. In this study, we loaded LLY-507, a potent inhibitor of SMYD2, a methyltransferase enzyme, on iron oxide nanoparticles (IONPs). The prepared n...

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Detalles Bibliográficos
Autores principales: Munawwar, Aasma, Sajjad, Amna, Rasul, Azhar, Sattar, Mehran, Jabeen, Farhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384399/
https://www.ncbi.nlm.nih.gov/pubmed/37513898
http://dx.doi.org/10.3390/ph16070986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384399/
https://www.ncbi.nlm.nih.gov/pubmed/37513898
http://dx.doi.org/10.3390/ph16070986

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