Cargando…

Recent Advances in Potential Health Benefits of Quercetin

Quercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, have been extensively studied. Its strong antioxidant properties enable it...

Descripción completa

Detalles Bibliográficos
Autores principales: Aghababaei, Fatemeh, Hadidi, Milad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384403/
https://www.ncbi.nlm.nih.gov/pubmed/37513932
http://dx.doi.org/10.3390/ph16071020
_version_ 1785081148787916800
author Aghababaei, Fatemeh
Hadidi, Milad
author_facet Aghababaei, Fatemeh
Hadidi, Milad
author_sort Aghababaei, Fatemeh
collection PubMed
description Quercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, have been extensively studied. Its strong antioxidant properties enable it to scavenge free radicals, reduce oxidative stress, and protect against cellular damage. Quercetin’s anti-inflammatory properties involve inhibiting the production of inflammatory cytokines and enzymes, making it a potential therapeutic agent for various inflammatory conditions. It also exhibits anticancer effects by inhibiting cancer cell proliferation and inducing apoptosis. Finally, quercetin has cardiovascular benefits such as lowering blood pressure, reducing cholesterol levels, and improving endothelial function, making it a promising candidate for preventing and treating cardiovascular diseases. This review provides an overview of the chemical structure, biological activities, and bioavailability of quercetin, as well as the different delivery systems available for quercetin. Incorporating quercetin-rich foods into the diet or taking quercetin supplements may be beneficial for maintaining good health and preventing chronic diseases. As research progresses, the future perspectives of quercetin appear promising, with potential applications in nutraceuticals, pharmaceuticals, and functional foods to promote overall well-being and disease prevention. However, further studies are needed to elucidate its mechanisms of action, optimize its bioavailability, and assess its long-term safety for widespread utilization.
format Online
Article
Text
id pubmed-10384403
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-103844032023-07-30 Recent Advances in Potential Health Benefits of Quercetin Aghababaei, Fatemeh Hadidi, Milad Pharmaceuticals (Basel) Review Quercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, have been extensively studied. Its strong antioxidant properties enable it to scavenge free radicals, reduce oxidative stress, and protect against cellular damage. Quercetin’s anti-inflammatory properties involve inhibiting the production of inflammatory cytokines and enzymes, making it a potential therapeutic agent for various inflammatory conditions. It also exhibits anticancer effects by inhibiting cancer cell proliferation and inducing apoptosis. Finally, quercetin has cardiovascular benefits such as lowering blood pressure, reducing cholesterol levels, and improving endothelial function, making it a promising candidate for preventing and treating cardiovascular diseases. This review provides an overview of the chemical structure, biological activities, and bioavailability of quercetin, as well as the different delivery systems available for quercetin. Incorporating quercetin-rich foods into the diet or taking quercetin supplements may be beneficial for maintaining good health and preventing chronic diseases. As research progresses, the future perspectives of quercetin appear promising, with potential applications in nutraceuticals, pharmaceuticals, and functional foods to promote overall well-being and disease prevention. However, further studies are needed to elucidate its mechanisms of action, optimize its bioavailability, and assess its long-term safety for widespread utilization. MDPI 2023-07-18 /pmc/articles/PMC10384403/ /pubmed/37513932 http://dx.doi.org/10.3390/ph16071020 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Aghababaei, Fatemeh
Hadidi, Milad
Recent Advances in Potential Health Benefits of Quercetin
title Recent Advances in Potential Health Benefits of Quercetin
title_full Recent Advances in Potential Health Benefits of Quercetin
title_fullStr Recent Advances in Potential Health Benefits of Quercetin
title_full_unstemmed Recent Advances in Potential Health Benefits of Quercetin
title_short Recent Advances in Potential Health Benefits of Quercetin
title_sort recent advances in potential health benefits of quercetin
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384403/
https://www.ncbi.nlm.nih.gov/pubmed/37513932
http://dx.doi.org/10.3390/ph16071020
work_keys_str_mv AT aghababaeifatemeh recentadvancesinpotentialhealthbenefitsofquercetin
AT hadidimilad recentadvancesinpotentialhealthbenefitsofquercetin