Detection of Age-Related Somatic Alterations in Canine Blood Using Next-Generation Sequencing-Based Liquid Biopsy: An Analysis of over 4800 Dogs

SIMPLE SUMMARY: In humans there is a biological phenomenon known as CHIP (clonal hematopoiesis of indeterminate potential) in which somatic (acquired) mutations cause blood cells of a certain type to grow disproportionately by making many copies (or “clones”) of themselves. Although most people who...

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Detalles Bibliográficos
Autores principales: Kruglyak, Kristina M., O’Kell, Allison L., Cohen, Todd A., Marshall, Maggie A., Ruiz-Perez, Carlos A., Marass, Francesco, Tynan, John A., Hicks, Susan C., Lytle, Katherine M., Phelps-Dunn, Ashley, Brandstetter, Gina, Warren, Chelsea D., DiMarzio, Lauren R., Rosentel, Michelle C., Wong, Lilian K., McLennan, Lisa M., Rafalko, Jill M., Grosu, Daniel S., Chibuk, Jason, Chorny, Ilya, McCleary-Wheeler, Angela L., Flory, Andi, Tsui, Dana W. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384417/
https://www.ncbi.nlm.nih.gov/pubmed/37505860
http://dx.doi.org/10.3390/vetsci10070455

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