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In-Silico Mining of the Toxins Database (T3DB) towards Hunting Prospective Candidates as ABCB1 Inhibitors: Integrated Molecular Docking and Lipid Bilayer-Enhanced Molecular Dynamics Study

Multidrug resistance (MDR) is one of the most problematic issues in chemotherapeutic carcinoma therapy. The ABCB1 transporter, a drug efflux pump overexpressed in cancer cells, has been thoroughly investigated for its association with MDR. Thus, discovering ABCB1 inhibitors can reverse the MDR in ca...

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Detalles Bibliográficos
Autores principales:	Ibrahim, Mahmoud A. A., Abdeljawaad, Khlood A. A., Abdelrahman, Alaa H. M., Sidhom, Peter A., Tawfeek, Ahmed M., Mekhemer, Gamal A. H., Abd El-Rahman, Mohamed K., Dabbish, Eslam, Shoeib, Tamer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384459/ https://www.ncbi.nlm.nih.gov/pubmed/37513931 http://dx.doi.org/10.3390/ph16071019

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