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Expression of E. coli FimH Enhances Trafficking of an Orally Delivered Lactobacillus acidophilus Vaccine to Immune Inductive Sites via Antigen-Presenting Cells

The development of lactic acid bacteria as mucosal vaccine vectors requires the identification of robust mucosal adjuvants to increase vaccine effectiveness. The E. coli type I fimbriae adhesion protein FimH is of interest as a mucosal adjuvant as it targets microfold (M) cells enhancing vaccine upt...

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Detalles Bibliográficos
Autores principales: Vilander, Allison C., Shelton, Kimberly, LaVoy, Alora, Dean, Gregg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384470/
https://www.ncbi.nlm.nih.gov/pubmed/37514978
http://dx.doi.org/10.3390/vaccines11071162

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