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Primary neuroendocrine tumor in the retroperitoneal cavity: A rare case report()

INTRODUCTION AND IMPORTANCE: Neuroendocrine tumors (NETs) are rare malignancies, accounting for a small percentage of gastrointestinal and bronchopulmonary cancers. Retroperitoneal NETs are infrequent and can be primary or metastatic. They are commonly metastatic rather than primary tumors, with pri...

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Autores principales: Nahle, Ali Alakbar, Hamdar, Hussein, Jawad, Ali, Obaied Alahmar, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384550/
https://www.ncbi.nlm.nih.gov/pubmed/37459696
http://dx.doi.org/10.1016/j.ijscr.2023.108506
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author Nahle, Ali Alakbar
Hamdar, Hussein
Jawad, Ali
Obaied Alahmar, Fadi
author_facet Nahle, Ali Alakbar
Hamdar, Hussein
Jawad, Ali
Obaied Alahmar, Fadi
author_sort Nahle, Ali Alakbar
collection PubMed
description INTRODUCTION AND IMPORTANCE: Neuroendocrine tumors (NETs) are rare malignancies, accounting for a small percentage of gastrointestinal and bronchopulmonary cancers. Retroperitoneal NETs are infrequent and can be primary or metastatic. They are commonly metastatic rather than primary tumors, with primary retroperitoneal NETs being exceptionally rare. CASE PRESENTATION: A 38-year-old woman presented with left flank pain persisting for one year, which had progressively worsened. Imaging revealed a large retroperitoneal mass exerting pressure on the stomach, spleen, liver, and upper pole of the left kidney. A biopsy of the tumor was done and the results were consistent with NET. The tumor, which measured approximately 19 × 12.5 × 11 cm, was surgically removed, and the pathological findings were consistent with the results of the biopsy prior to the surgery. CLINICAL DISCUSSION: Neuroendocrine tumors are rare and exhibit diverse characteristics based on location, size, hormone secretion, and metastasis. Retroperitoneal neuroendocrine tumors are typically metastatic and rarely primary. The extremely large size of the tumor in this case highlights the surgical challenges associated with retroperitoneal NETs. Imaging, such as CT and MRI, plays a crucial role in diagnosis. CONCLUSION: The study emphasizes the need to consider primary NETs as a possible cause of large retroperitoneal masses, especially if the tumor size is significant. Surgical resection is the primary treatment option with generally favorable outcomes. However, the size of the tumor can complicate treatment, and further research is needed to evaluate the effectiveness of postoperative adjuvant therapy and develop therapeutic approaches for recurrent NETs.
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spelling pubmed-103845502023-07-30 Primary neuroendocrine tumor in the retroperitoneal cavity: A rare case report() Nahle, Ali Alakbar Hamdar, Hussein Jawad, Ali Obaied Alahmar, Fadi Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Neuroendocrine tumors (NETs) are rare malignancies, accounting for a small percentage of gastrointestinal and bronchopulmonary cancers. Retroperitoneal NETs are infrequent and can be primary or metastatic. They are commonly metastatic rather than primary tumors, with primary retroperitoneal NETs being exceptionally rare. CASE PRESENTATION: A 38-year-old woman presented with left flank pain persisting for one year, which had progressively worsened. Imaging revealed a large retroperitoneal mass exerting pressure on the stomach, spleen, liver, and upper pole of the left kidney. A biopsy of the tumor was done and the results were consistent with NET. The tumor, which measured approximately 19 × 12.5 × 11 cm, was surgically removed, and the pathological findings were consistent with the results of the biopsy prior to the surgery. CLINICAL DISCUSSION: Neuroendocrine tumors are rare and exhibit diverse characteristics based on location, size, hormone secretion, and metastasis. Retroperitoneal neuroendocrine tumors are typically metastatic and rarely primary. The extremely large size of the tumor in this case highlights the surgical challenges associated with retroperitoneal NETs. Imaging, such as CT and MRI, plays a crucial role in diagnosis. CONCLUSION: The study emphasizes the need to consider primary NETs as a possible cause of large retroperitoneal masses, especially if the tumor size is significant. Surgical resection is the primary treatment option with generally favorable outcomes. However, the size of the tumor can complicate treatment, and further research is needed to evaluate the effectiveness of postoperative adjuvant therapy and develop therapeutic approaches for recurrent NETs. Elsevier 2023-07-13 /pmc/articles/PMC10384550/ /pubmed/37459696 http://dx.doi.org/10.1016/j.ijscr.2023.108506 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nahle, Ali Alakbar
Hamdar, Hussein
Jawad, Ali
Obaied Alahmar, Fadi
Primary neuroendocrine tumor in the retroperitoneal cavity: A rare case report()
title Primary neuroendocrine tumor in the retroperitoneal cavity: A rare case report()
title_full Primary neuroendocrine tumor in the retroperitoneal cavity: A rare case report()
title_fullStr Primary neuroendocrine tumor in the retroperitoneal cavity: A rare case report()
title_full_unstemmed Primary neuroendocrine tumor in the retroperitoneal cavity: A rare case report()
title_short Primary neuroendocrine tumor in the retroperitoneal cavity: A rare case report()
title_sort primary neuroendocrine tumor in the retroperitoneal cavity: a rare case report()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384550/
https://www.ncbi.nlm.nih.gov/pubmed/37459696
http://dx.doi.org/10.1016/j.ijscr.2023.108506
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