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ICP8-vhs- HSV-2 Vaccine Expressing B7 Costimulation Molecules Optimizes Safety and Efficacy against HSV-2 Infection in Mice

Herpes simplex virus 2 (HSV-2) causes most sexually transmitted genital ulcerative disease. No effective prophylactic vaccine is currently available. Replication-defective (ICP8-) HSV stimulates immune responses in animals without producing progeny virus, making it potentially useful as a safe form...

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Detalles Bibliográficos
Autores principales:	Korom, Maria, Wang, Hong, Bernier, Kaelin M., Geiss, Brian J., Morrison, Lynda A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384616/ https://www.ncbi.nlm.nih.gov/pubmed/37515256 http://dx.doi.org/10.3390/v15071570

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