Modification of the 4-Hydroxyphenylacetate-3-hydroxylase Substrate Pocket to Increase Activity towards Resveratrol

4-Hydroxyphenylacetate-3-hydroxylase (4HPA3H; EC 1.14.14.9) is a heterodimeric flavin-dependent monooxygenase complex that catalyzes the ortho-hydroxylation of resveratrol to produce piceatannol. Piceatannol has various health benefits and valuable applications in food, medicine, and cosmetics. Enha...

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Detalles Bibliográficos
Autores principales: Zhang, Qianchao, Jin, Yuning, Yang, Kai, Hu, Sheng, Lv, Changjiang, Huang, Jun, Mei, Jiaqi, Zhao, Weirui, Mei, Lehe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384689/
https://www.ncbi.nlm.nih.gov/pubmed/37513473
http://dx.doi.org/10.3390/molecules28145602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384689/
https://www.ncbi.nlm.nih.gov/pubmed/37513473
http://dx.doi.org/10.3390/molecules28145602

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