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Modification of the 4-Hydroxyphenylacetate-3-hydroxylase Substrate Pocket to Increase Activity towards Resveratrol
4-Hydroxyphenylacetate-3-hydroxylase (4HPA3H; EC 1.14.14.9) is a heterodimeric flavin-dependent monooxygenase complex that catalyzes the ortho-hydroxylation of resveratrol to produce piceatannol. Piceatannol has various health benefits and valuable applications in food, medicine, and cosmetics. Enha...
Autores principales: | Zhang, Qianchao, Jin, Yuning, Yang, Kai, Hu, Sheng, Lv, Changjiang, Huang, Jun, Mei, Jiaqi, Zhao, Weirui, Mei, Lehe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384689/ https://www.ncbi.nlm.nih.gov/pubmed/37513473 http://dx.doi.org/10.3390/molecules28145602 |
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