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Intraoral Drug Delivery: Highly Thiolated κ-Carrageenan as Mucoadhesive Excipient
Aim: This study aims to design a novel thiolated κ-carrageenan (κ-CA-SH) and evaluate its potential as an excipient for the design of mucoadhesive drug delivery systems. Methods: Native κ-carrageenan (κ-CA) was thiolated with phosphorous pentasulfide in sulfolane and characterized via (1)H NMR, FTIR...
Autores principales: | Kali, Gergely, Fürst, Andrea, Efiana, Nuri Ari, Dizdarević, Aida, Bernkop-Schnürch, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384811/ https://www.ncbi.nlm.nih.gov/pubmed/37514179 http://dx.doi.org/10.3390/pharmaceutics15071993 |
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