Image-Based Dosimetry in Dogs and Cross-Reactivity with Human Tissues of IGF2R-Targeting Human Antibody

Background: Osteosarcoma (OS) represents the most common primary bone tumor in humans and in companion dogs, being practically phenotypically identical. There is a need for effective treatments to extend the survival of patients with OS. Here, we examine the dosimetry in beagle dogs and cross-reacti...

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Detalles Bibliográficos
Autores principales: Allen, Kevin J. H., Kwon, Ohyun, Hutcheson, Matthew R., Grudzinski, Joseph J., Cain, Stuart M., Cruz, Frederic A., Vinayakamoorthy, Remitha M., Sun, Ying S., Fairley, Lindsay, Prabaharan, Chandra B., Dickinson, Ryan, MacDonald-Dickinson, Valerie, Uppalapati, Maruti, Bednarz, Bryan P., Dadachova, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384855/
https://www.ncbi.nlm.nih.gov/pubmed/37513891
http://dx.doi.org/10.3390/ph16070979

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