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cCPE Fusion Proteins as Molecular Probes to Detect Claudins and Tight Junction Dysregulation in Gastrointestinal Cell Lines, Tissue Explants and Patient-Derived Organoids

Claudins regulate paracellular permeability, contribute to epithelial polarization and are dysregulated during inflammation and carcinogenesis. Variants of the claudin-binding domain of Clostridium perfringens enterotoxin (cCPE) are highly sensitive protein ligands for generic detection of a broad s...

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Detalles Bibliográficos
Autores principales:	Waldow, Ayk, Beier, Laura-Sophie, Arndt, Janine, Schallenberg, Simon, Vollbrecht, Claudia, Bischoff, Philip, Farrera-Sal, Martí, Loch, Florian N., Bojarski, Christian, Schumann, Michael, Winkler, Lars, Kamphues, Carsten, Ehlen, Lukas, Piontek, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385049/ https://www.ncbi.nlm.nih.gov/pubmed/37514167 http://dx.doi.org/10.3390/pharmaceutics15071980

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