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An Overview of the Development and Preclinical Evaluation of Antibody–Drug Conjugates for Non-Oncological Applications

Typically, antibody–drug conjugates (ADCs) are made up of a humanized antibody and a small-molecule medication connected by a chemical linker. ADCs’ ability to deliver cytotoxic agents to the specific site with reduced side effects showed promising results in oncology. To date, fourteen ADCs have be...

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Detalles Bibliográficos
Autores principales: Pal, Lal Bahadur, Bule, Prajakta, Khan, Wahid, Chella, Naveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385119/
https://www.ncbi.nlm.nih.gov/pubmed/37513995
http://dx.doi.org/10.3390/pharmaceutics15071807