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Upregulation of Taurine Biosynthesis and Bile Acid Conjugation with Taurine through FXR in a Mouse Model with Human-like Bile Acid Composition

Taurine, the end product in the sulfur-containing amino acid pathway, is conjugated with bile acids (BAs) in the liver. The rate-limiting enzymes in both taurine synthesis and BA conjugation may be regulated by a nucleus receptor, FXR, that promotes BA homeostasis. However, it is controversial becau...

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Detalles Bibliográficos
Autores principales: Miyazaki, Teruo, Ueda, Hajime, Ikegami, Tadashi, Honda, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385265/
https://www.ncbi.nlm.nih.gov/pubmed/37512531
http://dx.doi.org/10.3390/metabo13070824