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Dissemination of the Omicron Variant and Its Sub-Lineages among Residents and Travelers in Its First Year of Emergence in Venezuela

The emergence of the SARS-CoV-2 Variant of Concern (VOC), Omicron, has been characterized by an explosive number of cases in almost every part of the world. The dissemination of different sub-lineages and recombinant genomes also led to several posterior waves in many countries. The circulation of t...

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Autores principales: Moros, Zoila C., Zambrano, José Luis, Sulbaran, Yoneira, Loureiro, Carmen L., Marulanda, Ernestina, Bracho, Francis, D’Angelo, Pierina, Rodríguez, Lieska, Liprandi, Ferdinando, Rangel, Héctor R., Jaspe, Rossana C., Pujol, Flor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385433/
https://www.ncbi.nlm.nih.gov/pubmed/37515148
http://dx.doi.org/10.3390/v15071460
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author Moros, Zoila C.
Zambrano, José Luis
Sulbaran, Yoneira
Loureiro, Carmen L.
Marulanda, Ernestina
Bracho, Francis
D’Angelo, Pierina
Rodríguez, Lieska
Liprandi, Ferdinando
Rangel, Héctor R.
Jaspe, Rossana C.
Pujol, Flor H.
author_facet Moros, Zoila C.
Zambrano, José Luis
Sulbaran, Yoneira
Loureiro, Carmen L.
Marulanda, Ernestina
Bracho, Francis
D’Angelo, Pierina
Rodríguez, Lieska
Liprandi, Ferdinando
Rangel, Héctor R.
Jaspe, Rossana C.
Pujol, Flor H.
author_sort Moros, Zoila C.
collection PubMed
description The emergence of the SARS-CoV-2 Variant of Concern (VOC), Omicron, has been characterized by an explosive number of cases in almost every part of the world. The dissemination of different sub-lineages and recombinant genomes also led to several posterior waves in many countries. The circulation of this VOC and its major sub-lineages (BA.1 to BA.5) was monitored in community cases and in international travelers returning to Venezuela by a rapid partial sequencing method. The specific sub-lineage assignment was performed by complete genome sequencing. Epidemic waves of SARS-CoV-2 cases were observed among international travelers during 2022, a situation not seen before December 2021. The succession of the Omicron VOC sub-lineages BA.1 to BA.5 occurred sequentially, except for BA.3, which was almost not detected. However, the sub-lineages generally circulated two months earlier in international travelers than in community cases. The diversity of Omicron sub-lineages found in international travelers was related to the one found in the USA, consistent with the most frequent destination of international travel from Venezuela this year. These differences are compatible with the delay observed sometimes in Latin American countries in the circulation of the different lineages of the Omicron VOC. Once the sub-lineages were introduced in the country, community transmission was responsible for generating a characteristic distribution of them, with a predominance of sub-lineages not necessarily similar to the one observed in travelers or neighboring countries.
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spelling pubmed-103854332023-07-30 Dissemination of the Omicron Variant and Its Sub-Lineages among Residents and Travelers in Its First Year of Emergence in Venezuela Moros, Zoila C. Zambrano, José Luis Sulbaran, Yoneira Loureiro, Carmen L. Marulanda, Ernestina Bracho, Francis D’Angelo, Pierina Rodríguez, Lieska Liprandi, Ferdinando Rangel, Héctor R. Jaspe, Rossana C. Pujol, Flor H. Viruses Article The emergence of the SARS-CoV-2 Variant of Concern (VOC), Omicron, has been characterized by an explosive number of cases in almost every part of the world. The dissemination of different sub-lineages and recombinant genomes also led to several posterior waves in many countries. The circulation of this VOC and its major sub-lineages (BA.1 to BA.5) was monitored in community cases and in international travelers returning to Venezuela by a rapid partial sequencing method. The specific sub-lineage assignment was performed by complete genome sequencing. Epidemic waves of SARS-CoV-2 cases were observed among international travelers during 2022, a situation not seen before December 2021. The succession of the Omicron VOC sub-lineages BA.1 to BA.5 occurred sequentially, except for BA.3, which was almost not detected. However, the sub-lineages generally circulated two months earlier in international travelers than in community cases. The diversity of Omicron sub-lineages found in international travelers was related to the one found in the USA, consistent with the most frequent destination of international travel from Venezuela this year. These differences are compatible with the delay observed sometimes in Latin American countries in the circulation of the different lineages of the Omicron VOC. Once the sub-lineages were introduced in the country, community transmission was responsible for generating a characteristic distribution of them, with a predominance of sub-lineages not necessarily similar to the one observed in travelers or neighboring countries. MDPI 2023-06-28 /pmc/articles/PMC10385433/ /pubmed/37515148 http://dx.doi.org/10.3390/v15071460 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Moros, Zoila C.
Zambrano, José Luis
Sulbaran, Yoneira
Loureiro, Carmen L.
Marulanda, Ernestina
Bracho, Francis
D’Angelo, Pierina
Rodríguez, Lieska
Liprandi, Ferdinando
Rangel, Héctor R.
Jaspe, Rossana C.
Pujol, Flor H.
Dissemination of the Omicron Variant and Its Sub-Lineages among Residents and Travelers in Its First Year of Emergence in Venezuela
title Dissemination of the Omicron Variant and Its Sub-Lineages among Residents and Travelers in Its First Year of Emergence in Venezuela
title_full Dissemination of the Omicron Variant and Its Sub-Lineages among Residents and Travelers in Its First Year of Emergence in Venezuela
title_fullStr Dissemination of the Omicron Variant and Its Sub-Lineages among Residents and Travelers in Its First Year of Emergence in Venezuela
title_full_unstemmed Dissemination of the Omicron Variant and Its Sub-Lineages among Residents and Travelers in Its First Year of Emergence in Venezuela
title_short Dissemination of the Omicron Variant and Its Sub-Lineages among Residents and Travelers in Its First Year of Emergence in Venezuela
title_sort dissemination of the omicron variant and its sub-lineages among residents and travelers in its first year of emergence in venezuela
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385433/
https://www.ncbi.nlm.nih.gov/pubmed/37515148
http://dx.doi.org/10.3390/v15071460
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