The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?

The ketogenic diet (KD) is, nowadays, considered an interesting nutritional approach for weight loss and improvement in insulin resistance. Nevertheless, most of the studies available in the literature do not allow a clear distinction between its effects on insulin sensitivity per se, and the effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Paoli, Antonio, Bianco, Antonino, Moro, Tatiana, Mota, Joao Felipe, Coelho-Ravagnani, Christianne F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385501/
https://www.ncbi.nlm.nih.gov/pubmed/37513538
http://dx.doi.org/10.3390/nu15143120
_version_ 1785081423342862336
author Paoli, Antonio
Bianco, Antonino
Moro, Tatiana
Mota, Joao Felipe
Coelho-Ravagnani, Christianne F.
author_facet Paoli, Antonio
Bianco, Antonino
Moro, Tatiana
Mota, Joao Felipe
Coelho-Ravagnani, Christianne F.
author_sort Paoli, Antonio
collection PubMed
description The ketogenic diet (KD) is, nowadays, considered an interesting nutritional approach for weight loss and improvement in insulin resistance. Nevertheless, most of the studies available in the literature do not allow a clear distinction between its effects on insulin sensitivity per se, and the effects of weight loss induced by KDs on insulin sensitivity. In this review, we discuss the scientific evidence on the direct and weight loss mediated effects of KDs on glycemic status in humans, describing the KD’s biochemical background and the underlying mechanisms.
format Online
Article
Text
id pubmed-10385501
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-103855012023-07-30 The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg? Paoli, Antonio Bianco, Antonino Moro, Tatiana Mota, Joao Felipe Coelho-Ravagnani, Christianne F. Nutrients Review The ketogenic diet (KD) is, nowadays, considered an interesting nutritional approach for weight loss and improvement in insulin resistance. Nevertheless, most of the studies available in the literature do not allow a clear distinction between its effects on insulin sensitivity per se, and the effects of weight loss induced by KDs on insulin sensitivity. In this review, we discuss the scientific evidence on the direct and weight loss mediated effects of KDs on glycemic status in humans, describing the KD’s biochemical background and the underlying mechanisms. MDPI 2023-07-12 /pmc/articles/PMC10385501/ /pubmed/37513538 http://dx.doi.org/10.3390/nu15143120 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Paoli, Antonio
Bianco, Antonino
Moro, Tatiana
Mota, Joao Felipe
Coelho-Ravagnani, Christianne F.
The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?
title The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?
title_full The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?
title_fullStr The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?
title_full_unstemmed The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?
title_short The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?
title_sort effects of ketogenic diet on insulin sensitivity and weight loss, which came first: the chicken or the egg?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385501/
https://www.ncbi.nlm.nih.gov/pubmed/37513538
http://dx.doi.org/10.3390/nu15143120
work_keys_str_mv AT paoliantonio theeffectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT biancoantonino theeffectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT morotatiana theeffectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT motajoaofelipe theeffectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT coelhoravagnanichristiannef theeffectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT paoliantonio effectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT biancoantonino effectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT morotatiana effectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT motajoaofelipe effectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg
AT coelhoravagnanichristiannef effectsofketogenicdietoninsulinsensitivityandweightlosswhichcamefirstthechickenortheegg

Ejemplares similares