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In Silico Substrate-Binding Profiling for SARS-CoV-2 Main Protease (M(pro)) Using Hexapeptide Substrates

The SARS-CoV-2 main protease (M(pro)) is essential for the life cycle of the COVID-19 virus. It cleaves the two polyproteins at 11 positions to generate mature proteins for virion formation. The cleavage site on these polyproteins is known to be Leu-Gln↓(Ser/Ala/Gly). A range of hexapeptides that fo...

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Detalles Bibliográficos
Autores principales:	Zabo, Sophakama, Lobb, Kevin Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385622/ https://www.ncbi.nlm.nih.gov/pubmed/37515167 http://dx.doi.org/10.3390/v15071480

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