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Quetiapine Albumin Nanoparticles as an Efficacious Platform for Brain Deposition and Potentially Improved Antipsychotic Activity
Quetiapine (QP) is a second-generation short-acting antipsychotic drug extensively metabolized in the liver, producing pharmacologically inactive metabolites and leading to diminished bioavailability. Therefore, this study aimed to develop an intravenous QP albumin nanoparticles (NPs) system for imp...
Autores principales: | Abdel-Bar, Hend Mohamed, Tulbah, Alaa S., Darwish, Hany W., Salama, Rania, Naguib, Ibrahim A., Yassin, Heba A., Abo El-Enin, Hadel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385742/ https://www.ncbi.nlm.nih.gov/pubmed/37513972 http://dx.doi.org/10.3390/pharmaceutics15071785 |
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