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Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design

Artificial intelligence (AI) has emerged as a powerful tool that harnesses anthropomorphic knowledge and provides expedited solutions to complex challenges. Remarkable advancements in AI technology and machine learning present a transformative opportunity in the drug discovery, formulation, and test...

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Autores principales: Vora, Lalitkumar K., Gholap, Amol D., Jetha, Keshava, Thakur, Raghu Raj Singh, Solanki, Hetvi K., Chavda, Vivek P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385763/
https://www.ncbi.nlm.nih.gov/pubmed/37514102
http://dx.doi.org/10.3390/pharmaceutics15071916
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author Vora, Lalitkumar K.
Gholap, Amol D.
Jetha, Keshava
Thakur, Raghu Raj Singh
Solanki, Hetvi K.
Chavda, Vivek P.
author_facet Vora, Lalitkumar K.
Gholap, Amol D.
Jetha, Keshava
Thakur, Raghu Raj Singh
Solanki, Hetvi K.
Chavda, Vivek P.
author_sort Vora, Lalitkumar K.
collection PubMed
description Artificial intelligence (AI) has emerged as a powerful tool that harnesses anthropomorphic knowledge and provides expedited solutions to complex challenges. Remarkable advancements in AI technology and machine learning present a transformative opportunity in the drug discovery, formulation, and testing of pharmaceutical dosage forms. By utilizing AI algorithms that analyze extensive biological data, including genomics and proteomics, researchers can identify disease-associated targets and predict their interactions with potential drug candidates. This enables a more efficient and targeted approach to drug discovery, thereby increasing the likelihood of successful drug approvals. Furthermore, AI can contribute to reducing development costs by optimizing research and development processes. Machine learning algorithms assist in experimental design and can predict the pharmacokinetics and toxicity of drug candidates. This capability enables the prioritization and optimization of lead compounds, reducing the need for extensive and costly animal testing. Personalized medicine approaches can be facilitated through AI algorithms that analyze real-world patient data, leading to more effective treatment outcomes and improved patient adherence. This comprehensive review explores the wide-ranging applications of AI in drug discovery, drug delivery dosage form designs, process optimization, testing, and pharmacokinetics/pharmacodynamics (PK/PD) studies. This review provides an overview of various AI-based approaches utilized in pharmaceutical technology, highlighting their benefits and drawbacks. Nevertheless, the continued investment in and exploration of AI in the pharmaceutical industry offer exciting prospects for enhancing drug development processes and patient care.
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spelling pubmed-103857632023-07-30 Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design Vora, Lalitkumar K. Gholap, Amol D. Jetha, Keshava Thakur, Raghu Raj Singh Solanki, Hetvi K. Chavda, Vivek P. Pharmaceutics Review Artificial intelligence (AI) has emerged as a powerful tool that harnesses anthropomorphic knowledge and provides expedited solutions to complex challenges. Remarkable advancements in AI technology and machine learning present a transformative opportunity in the drug discovery, formulation, and testing of pharmaceutical dosage forms. By utilizing AI algorithms that analyze extensive biological data, including genomics and proteomics, researchers can identify disease-associated targets and predict their interactions with potential drug candidates. This enables a more efficient and targeted approach to drug discovery, thereby increasing the likelihood of successful drug approvals. Furthermore, AI can contribute to reducing development costs by optimizing research and development processes. Machine learning algorithms assist in experimental design and can predict the pharmacokinetics and toxicity of drug candidates. This capability enables the prioritization and optimization of lead compounds, reducing the need for extensive and costly animal testing. Personalized medicine approaches can be facilitated through AI algorithms that analyze real-world patient data, leading to more effective treatment outcomes and improved patient adherence. This comprehensive review explores the wide-ranging applications of AI in drug discovery, drug delivery dosage form designs, process optimization, testing, and pharmacokinetics/pharmacodynamics (PK/PD) studies. This review provides an overview of various AI-based approaches utilized in pharmaceutical technology, highlighting their benefits and drawbacks. Nevertheless, the continued investment in and exploration of AI in the pharmaceutical industry offer exciting prospects for enhancing drug development processes and patient care. MDPI 2023-07-10 /pmc/articles/PMC10385763/ /pubmed/37514102 http://dx.doi.org/10.3390/pharmaceutics15071916 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Vora, Lalitkumar K.
Gholap, Amol D.
Jetha, Keshava
Thakur, Raghu Raj Singh
Solanki, Hetvi K.
Chavda, Vivek P.
Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design
title Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design
title_full Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design
title_fullStr Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design
title_full_unstemmed Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design
title_short Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design
title_sort artificial intelligence in pharmaceutical technology and drug delivery design
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385763/
https://www.ncbi.nlm.nih.gov/pubmed/37514102
http://dx.doi.org/10.3390/pharmaceutics15071916
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